Clinical trial Recruiting at 2 sites Interventional Ages 18 and up

Maintaining Independence and Sobriety through Systems Integration, Outreach, and Networking-Criminal Justice (MISSION-CJ) for re-entry

Official title: Supporting Treatment Access and Recovery in Re-entry (STAR-R)

Run by University of Massachusetts, Worcester · NCT07555145 · Data updated 2026-11-12

This trial tests a multicomponent program called MISSION-CJ with Peer Linkage Support to help adults released from two Massachusetts jails who have both mental health and substance use disorders.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment240 (estimated)
SponsorUniversity of Massachusetts, Worcester
Academic / other
Locations2 sites (Northampton, Massachusetts and 1 other locations)
StatusRecruiting
StartedOctober 29, 2026
Main results expectedMay 31, 2030
Study endsAugust 31, 2030
Registry record updatedNovember 9, 2026
Trial IDNCT07555145 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 and older released from participating Massachusetts jails who have a documented co-occurring substance use and mental health disorder and can read/write in English.

Probably not a fit

Individuals without a co-occurring disorder or who are acutely suicidal or psychotic may not benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study will test a cross-disciplinary, multicomponent re-entry intervention that combines COD treatment, prosocial and recovery services, and assertive outreach for up to six months after jail release. It aims to improve engagement in treatment, behavioral health outcomes, and reduce re-incarceration, while examining mediators, moderators, and an economic analysis. The trial builds on four open pilots showing promise in treatment engagement and reduced recidivism and will utilize a structured manual, workbook, treatment planning tool, and fidelity measures. Participants are adults released from participating jails in Massachusetts who have co-occurring substance use and mental health disorders. The study will compare full MISSION-CJ with Peer Linkage Support to standard re-entry approaches, across multiple sites with robust data collection on outcomes and implementation factors.

Why it matters

Potential benefit: If successful, participants may experience better mental health and substance use treatment engagement and lower risk of relapse and reincarceration.

How similar studies have gone: Past MISSION-CJ pilots demonstrated higher treatment engagement, better behavioral health outcomes, and lower recidivism in similar populations.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years or older;
* Proficient in reading and writing in the English language;
* Are released from one of the participating jail/s; and
* Have a current co-occurring substance use and mental health disorder, which includes both any substance use disorder (including alcohol) and mental health disorder (including depression, anxiety, trauma related disorders, bipolar, and/or schizophrenia) as documented by the participating jails.

Exclusion Criteria:

* Are acutely suicidal based on the CSSRS; or
* Are acutely psychotic (as this would require a higher level of care) based on SCID-5-RV.

Where it's running

  • Hampshire County Jail and House of Correction
    Northampton, Massachusetts, United States
    Recruiting
  • Worceseter County Jail and House of Correction
    West Boylston, Massachusetts, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.