Lung health check with low-dose CT and AI help to find cancer and heart-lung conditions
Official title: GALACTIC 1 - Glasgow Low-dose CT and AI-based Diagnostics to Case Find Lung Cancer and Other Cardio-respiratory Long-term Conditions - Feasibility Study
Run by NHS Greater Glasgow and Clyde · NCT07372508 · Data updated 2026-11-12
This study tests a lung cancer screening program that adds heart and breathing tests in one visit for people 55-74 who smoke or have heavy smoking history.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 55 Years to 74 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | NHS Greater Glasgow and Clyde Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Glasgow) |
| Status | Recruiting |
| Started | May 26, 2026 |
| Main results expected | December 2, 2026 |
| Study ends | September 2, 2028 |
| Registry record updated | June 23, 2026 |
| Trial ID | NCT07372508 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 55–74, resident in the South Sector NHS GG&C, with current or recent heavy smoking history (20+ pack-years) and able to consent.
✕Probably not a fit
Individuals without a high smoking history, unable to consent, or those who have a recent CT scan or other exclusion criteria may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This feasibility study evaluates a lung cancer screening pathway that uses low-dose CT scans, with added heart and breathing assessments, in a single clinic visit. The approach targets adults aged 55–74 with a substantial smoking history living in the South Sector NHS GG&C area. Participants receive a quick LDCT scan to detect lung cancer early, with the goal of identifying additional cardio-respiratory conditions. The study will assess how practical and useful these added tests are within the existing screening program. No efficacy conclusions are intended at this stage, but feasibility, workflow impact, and potential benefits will be explored.
Why it matters
Potential benefit: If successful, the approach could improve early detection of lung cancer and reveal other heart-lung conditions during a single screening visit.
How similar studies have gone: Previous lung cancer LDCT screening programs have shown value; this study adds additional tests to explore incremental utility in a feasibility framework.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Resident in South Sector NHS GG\&C. * Capacity to undertake informed consent. * No active cancer other than non-melanoma skin cancer, monitored localised prostate cancer or localised treated breast cancer. * Aged 55-74 at date of invitation. * Smoking history: current tobacco smoker or ex-smoker with \>20 pack year history and \<15 years from quit date. Exclusion Criteria: * CT thorax scan undertaken in prior 12 months. * Does not have capacity to give consent (standard criteria for assessing capacity apply). * Aged \<55 or \>74 years of age at date of invitation * Weight exceeds restrictions for scanner (\>200kg). * Unable to lie flat. * People who are pregnant. * Active symptoms of possible lung cancer
Where it's running
-
Queen Elizabeth University Hospital
Glasgow, United Kingdom Recruiting
Study contacts
- Principal investigator: Chris Carlin — Nhsggc
- Study coordinator: Clare Dolan
- Email: clare.dolan3@nhs.scot
- Phone: 0141 314 4328
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.