Lung Health and the Microbiome in Botswana: The Go-hema Cohort

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective cohort study in Botswana that aims to characterize abnormal lung function patterns and explore associations between the host microbiome and COPD outcomes. Researchers will use multi-omics approaches to analyze data from adults with and without HIV to understand how microbiome interactions may influence lung health and disease progression. The study focuses on data collection from local health facilities in Gaborone to improve understanding of COPD in a population underrepresented in current research. Findings could help inform more equitable approaches to COPD prevention and therapy for populations similar to Botswana.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults 35 years of age or older
* In case at a clinic in Botswana
* Documented HIV status
* Ability to provide informed consent

Exclusion Criteria:

* Respiratory infection in the prior 4 weeks
* Active pulmonary tuberculosis
* Inability to perform spirometry including eye, abdominal, or
* Thoracic surgery or myocardial infarction in the prior 6 weeks
* Pregnancy

Where it's running

• Local Health Facilities in Gaborone
  Gaborone, Botswana Recruiting

Study contacts

• Principal investigator: Robert Gross, Medical — University of Pennsylvania
• Study coordinator: Relebogile Thipe, Nursing
• Email: thre2001@gmail.com
• Phone: +2673170933

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.