Measuring the properties of lung secretions in patients with obstructive pulmonary disease
Official title: VLM-2: Measurement of Viscoelastic Properties of Bronchopulmonary Secretions.
Run by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · NCT03888300 · Data updated 2026-11-12
This study is testing how the thickness and stickiness of mucus in the lungs changes in people with obstructive pulmonary disease before and after they do breathing exercises or physiotherapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Cliniques universitaires Saint-Luc- Université Catholique de Louvain Academic / other |
| Locations | 1 site (Brussels) |
| Status | Recruiting |
| Started | August 1, 2019 |
| Main results expected | August 1, 2027 |
| Study ends | August 1, 2027 |
| Registry record updated | April 29, 2026 |
| Trial ID | NCT03888300 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with obstructive pulmonary disease.
✕Probably not a fit
Patients without obstructive pulmonary disease may not receive any benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This experimental study aims to compare the viscoelastic properties of bronchial secretions in patients with obstructive pulmonary disease. It will also assess changes in these properties before and after the application of respiratory physiotherapy or exercise. Sputum samples will be collected from participants using standard clinical methods, and the analysis will take place at the Saint-Luc University Clinic in Brussels.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for patients with obstructive pulmonary disease by enhancing understanding of bronchial secretions.
How similar studies have gone: While similar studies have explored bronchial secretions, this specific approach to measuring viscoelastic properties is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * obstructive pulmonary disease Exclusion Criteria: * none
Where it's running
-
Cliniques universitaires Saint-Luc
Brussels, Belgium Recruiting
Study contacts
- Principal investigator: Gregory Reychler, PT, PhD — Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- Study coordinator: Gregory Reychler, PT, PhD
- Email: gregory.reychler@uclouvain.be
- Phone: +3227642316
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.