Lung cancer screening for workers exposed to harmful substances

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the feasibility of lung cancer screening using low-dose chest CT scans in a high-risk population of smokers aged 55 to 74 who have been exposed to occupational lung carcinogens. It aims to assess the organization of screening activities, the validity of self-administered questionnaires for identifying high-risk individuals, and the effectiveness of lung cancer detection methods. The study will also monitor smoking cessation rates among participants over a two-year period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Subjects at high risk of lung cancer: current smokers smoking 30 pack-years or more or ex-smokers smoking 30 pack-years or more and who have quit smoking for less than 15 years and currently or previously occupationally exposed to lung carcinogens. With an algorithm for determination of minimal duration of exposure to occupational carcinogens (according to the type and duration of occupational lung carcinogens)

Exclusion Criteria:

* Presence of clinical signs of lung cancer
* Subjects with a history of lung cancer
* Presence of serious short-term life-threatening comorbidities
* Absence of occupational exposure to lung carcinogens according to the predefined criteria
* Subjects already included in another prospective cohort study
* Subjects already assessed by chest CT scan during the previous year
* No tobacco exposure or insufficient tobacco exposure or smoking cessation for more than 15 years.

Where it's running

• Centre Hospitalier Universitaire de Bordeaux
  Bordeaux, France Recruiting
• Centre Hospitalier Intercommunal de Créteil
  Créteil, France Recruiting
• Université de Bordeaux
  Bordeaux, France Active not recruiting
• Centre Hospitalier Universitaire de Brest
  Brest, France Not yet recruiting
• Centre Hospitalier Universitaire de Caen
  Caen, France Not yet recruiting
• Centre Hospitalier Universitaire de Rennes
  Rennes, France Not yet recruiting

Study contacts

• Principal investigator: Jean-Claude Pairon, Pr — Centre Hospitalier Interconnmunal de Créteil
• Study coordinator: Jean-Claude Pairon, Pr
• Email: JC.Pairon@chicreteil.fr
• Phone: 157022093

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.