LUCINAE Registry: Thoracic Cancers in Pregnancy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The LUCINAE Registry is an international, multicenter observational effort that combines retrospective and prospective data to describe patients with thoracic cancers who are pregnant or become pregnant around cancer treatment. It includes women diagnosed during pregnancy, women who become pregnant during/after cancer, and men undergoing cancer treatment at conception. Data cover clinical characteristics, diagnostics, treatments, and maternal and fetal outcomes to inform future guidelines. The study uses two cohorts: retrospective data from medical records and prospective data with ongoing follow-up. Results aim to enhance understanding and support development of clinical recommendations for thoracic cancers in pregnancy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 1\. All patients with a diagnosis of thoracic cancer (including lung cancer, mesothelioma, thymic epithelial tumors, neuroendocrine tumors or sarcoma of the thorax and other rare thoracic entities) and pregnancy (positive pregnancy test) including:

  1. Patients receiving a diagnosis of thoracic cancer during pregnancy
  2. Patients who became pregnant while having active thoracic cancer
  3. Patients previously treated for a thoracic cancer and becoming pregnant in the 5 years following end of treatment OR Men with a diagnosis of thoracic cancer (including lung cancer, mesothelioma, thymic epithelial tumors, neuroendocrine tumors or sarcoma of the thorax and other rare thoracic entities), who were undergoing active oncological treatment at the time their partner conceived their child.
* 2\. Available information about pregnancy outcomes
* 3\. Age ≥ 18 years

Exclusion Criteria:

* 1\. Patient missing data about thoracic cancer stage and diagnosis
* 2\. For retrospective patients, documented refusal to the use of clinical data for research purposes

Where it's running

• Kantonsspital Baden
  Baden, Switzerland Recruiting
• Istituto Oncologico della Svizzera Italiana (IOSI)
  Bellinzona, Switzerland Recruiting
• Geneva University Hospital (HUG)
  Geneva, Switzerland Recruiting
• Kantonsspital Winterthur
  Winterthur, Switzerland Recruiting

Study contacts

• Study coordinator: Martina Imbimbo
• Email: Martina.Imbimbo@eoc.ch
• Phone: +41918119631

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.