Low-intensity magnetic stimulation for treating major depression

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effects of low-intensity transcranial magnetic stimulation (TMS) on patients with major depressive disorder (MDD). The study aims to determine whether TMS can reduce depressive symptoms and alter levels of specific biomarkers, including 5-hydroxyindoleacetic acid and brain-derived neurotrophic factor. Participants will undergo TMS treatment while their symptoms and biomarker levels are monitored before and after the intervention. The safety of the procedure will also be assessed through follow-up evaluations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 60 years.
* Both sexes.
* Those who have a diagnosis of MDD previously made by the treating psychiatrist (considering time since diagnosis and recurrence of episodes).
* Those who continue with their respective treatment and attend follow-up consultations at the health facility.
* Those who do not have a history of epilepsy, schizophrenia, neurosurgeries.
* Those who do not have metal plates anywhere in the skull, neck, chest and shoulder.
* Those who do not use pacemakers.
* Those who do not take hormone substitutes.
* Those who agree to participate in the research.

Exclusion Criteria:

* Those who are pregnant.

Where it's running

• High Specialty Medical Unit No. 1, Bajío. Mexican Social Security Institute
  León, Guanajuato, Mexico Recruiting

Study contacts

• Principal investigator: Olga E Escobar Florez, Master of Medical Sciences — Universidad de Guanajuato
• Study coordinator: Olga E Escobar Florez, Master of Medical Sciences
• Email: oe.escobarflorez@ugto.mx
• Phone: +524773703795

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.