Low-dose galactose added to a meal to test blood sugar control

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study uses a crossover design to compare glucose kinetics after a standard 75 g glucose load with and without galactose, and with fructose as a comparator. State-of-the-art dual stable isotope tracing will track how glucose enters the bloodstream, how the liver releases sugar, and how muscles take up glucose. The goal is to see if galactose slows glucose appearance from the gut or liver or enhances glucose disposal in tissues. Results will clarify whether galactose can modulate postprandial glycemia in normoglycemic adults. The study is led by the University of Bath with collaboration from the University of Birmingham and Arla Foods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: 18 years and above;
* Normoglycaemic (fasting glucose \<6.1 mmol/L)
* Body mass index: 18.5-30 kg/m2

Exclusion Criteria:

* weight instability (\>5% change within last 3 months);
* pregnant or lactating;
* following a very low-carbohydrate (ketogenic) diet;
* diagnosis of diabetes or prediabetes, or any other metabolic disease;
* dietary intolerances or allergies, or to any other study procedures;
* disorders in the ability to metabolise galactose or fructose (e.g., galactosemias);
* diagnosis of any gastrointestinal disorders;
* any other condition/medications that could introduce bias;
* unable to understand and follow study procedures

Where it's running

• University of Bath
  Bath, United Kingdom Recruiting

Study contacts

• Study coordinator: Lucy Merrell, PhD
• Email: lhm31@bath.ac.uk
• Phone: +441225385518

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Timing broccoli sprout intake to see if it boosts endurance performance

  This study tests whether taking a broccoli sprout drink at different times before cycling can improve performance and recovery in healthy, endurance-trained adults.

  Recruiting The Swedish School of Sport and Health Sciences · Stockholm, Stockholm County · NCT07461194

• Tracking how labeled glucose is used by immune cells in real time

  Adults will receive a short infusion of safe, non-radioactive labeled glucose while researchers take blood immune cells to see how those cells use glucose for energy and as building material.

  Recruiting Vanderbilt University Medical Center · Nashville, Tennessee · NCT06930976

• Comparing two types of dextrose injections for knee osteoarthritis treatment

  This study is testing whether a special type of knee injection guided by MRI works better than a standard injection for people aged 45 to 80 with knee osteoarthritis.

  Recruiting Shin Kong Wu Ho-Su Memorial Hospital · Taipei · NCT06755697

• Breaking up long periods of sitting to improve heart and metabolic health

  This study is testing how often and how long people should take breaks from sitting to see if it can help improve their heart and metabolic health.

  Recruiting Columbia University · New York, New York · NCT05353322

• AMX0035 in adults with Type 1 Diabetes

  This study tests whether 24 weeks of the oral medication AMX0035 help improves metabolic health in adults with Type 1 Diabetes compared with a placebo.

  Recruiting Phase 2 University of Washington · Seattle, Washington and 1 other locations · NCT07699380

• Orforglipron for Type 2 Diabetes in Ramadan Fasters

  This study tests whether orforglipron helps people with type 2 diabetes who fast during Ramadan, to see if it improves blood sugar control safely.

  Recruiting at 33 sites Phase 3 Eli Lilly and Company · Agra and 39 other locations · NCT07613307

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.