Low Blood Flow Restriction Training for Nonspecific Low Back Pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, controlled intervention study examines the effects of low-load blood flow restriction training added to conventional physical therapy for adults with chronic nonspecific low back pain. Participants aged 18 to 45 with pain persisting more than 12 weeks and measurable hamstring weakness will be randomized to receive either standard physical therapy alone or with low-load BFR training. The study aims to determine changes in hamstring strength, pain intensity, and functional disability. Exclusion criteria include imaging-confirmed anatomical pathology, prior hip or lower-extremity surgical conditions, and history of thromboembolic disease. The lead sponsor is Riphah International University, with the National Institute Of Rehabilitation Medicine in Islamabad as the site.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Participants falling in this category would be recruited into the study.

1. Both gender
2. Age is between 18-45 years
3. Individuals with pain localized posteriorly below the costal margin and above the inferior gluteal folds for more than 12 weeks
4. A score greater than or equal to 4/10 on Numeric Pain Rating Scale (NPRS)
5. Hamstring muscle strength graded between (3- to 4) on MMT
6. Proximal thigh circumference between (27.0 cm to 56.0 cm), measured 10cm below the inguinal crease
7. Eligible for BFR training as per the Blood Flow Restriction Blood Flow Training Questionnaire

Exclusion Criteria:

Participants falling in this category would be excluded from the study.

1. Patients of spinal stenosis, disc herniation spondylolisthesis, spondylosis or osteoporosis will be excluded
2. Participants had a history of hip or lower extremity pathology requiring medical or surgical intervention.
3. History of venous thromboembolism (VTE), clotting or other hematologic disorder
4. Peripheral arterial disease, hypertension (blood pressure \>140/90 mm Hg), coronary artery disease
5. Current Pregnancy
6. Patients who had difficulties in exercise performance due to mental problems.
7. Spinal cord infection like Cauda equina syndrome

Where it's running

• National Institute Of Rehabilitation Medicine G-8/2, Islamabad
  Islamabad, Pakistan Recruiting

Study contacts

• Principal investigator: Kinza Anwar, Ms-Ompt — Riphah International University
• Study coordinator: Kinza Anwar, Ms-Ompt
• Email: kinza.anwar@riphah.edu.pk
• Phone: +92-3239735427

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.