Longitudinal study of CAR-T cell therapy in patients with blood cancers
Official title: National Longitudinal Cohort of Hematological Diseases (NICHE) - CART
Run by Institute of Hematology & Blood Diseases Hospital, China · NCT06607289 · Data updated 2026-11-12
This study looks at how well CAR-T cell therapy works for Chinese patients with blood cancers by gathering information from those who have already received this treatment.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Institute of Hematology & Blood Diseases Hospital, China Academic / other |
| Drugs / interventions | CAR-T |
| Locations | 1 site (Tianjin, Tianjin Municipality) |
| Status | Recruiting |
| Started | June 1, 2021 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2032 |
| Registry record updated | June 17, 2025 |
| Trial ID | NCT06607289 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients with clinically diagnosed hematological malignancies who have undergone CAR-T cell therapy.
✕Probably not a fit
Patients who do not have hematological malignancies or have not received CAR-T cell therapy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort study aims to investigate the effectiveness of CAR-T cell therapy in Chinese patients diagnosed with hematological malignancies. It will collect patient-level data from a consortium of Phase IV clinical trials and real-world studies to create a comprehensive cohort. The study will include patients who have received CAR-T cell therapy and are part of an existing longitudinal cohort focused on hematological diseases. The goal is to better understand the outcomes and impacts of this innovative treatment approach.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the effectiveness and safety of CAR-T cell therapy for patients with blood cancers.
How similar studies have gone: Other studies have shown promising results with CAR-T cell therapy in hematological malignancies, indicating a potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with clinically diagnosed hematologic malignancies * Patients treated with CAR-T cell therapy * Signed the informed consent form
Where it's running
-
Institute of Hematology & Blood Diseases Hospital
Tianjin, Tianjin Municipality, China Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.