Clinical trial Recruiting at 1 site Observational

Longitudinal study of CAR-T cell therapy in patients with blood cancers

Official title: National Longitudinal Cohort of Hematological Diseases (NICHE) - CART

Run by Institute of Hematology & Blood Diseases Hospital, China · NCT06607289 · Data updated 2026-11-12

This study looks at how well CAR-T cell therapy works for Chinese patients with blood cancers by gathering information from those who have already received this treatment.

More Hematological Malignancies trials

Quick facts

Study typeObservational
SexAll
Enrollment1000 (estimated)
SponsorInstitute of Hematology & Blood Diseases Hospital, China
Academic / other
Drugs / interventionsCAR-T
Locations1 site (Tianjin, Tianjin Municipality)
StatusRecruiting
StartedJune 1, 2021
Main results expectedDecember 31, 2026
Study endsDecember 31, 2032
Registry record updatedJune 17, 2025
Trial IDNCT06607289 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with clinically diagnosed hematological malignancies who have undergone CAR-T cell therapy.

Probably not a fit

Patients who do not have hematological malignancies or have not received CAR-T cell therapy may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort study aims to investigate the effectiveness of CAR-T cell therapy in Chinese patients diagnosed with hematological malignancies. It will collect patient-level data from a consortium of Phase IV clinical trials and real-world studies to create a comprehensive cohort. The study will include patients who have received CAR-T cell therapy and are part of an existing longitudinal cohort focused on hematological diseases. The goal is to better understand the outcomes and impacts of this innovative treatment approach.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the effectiveness and safety of CAR-T cell therapy for patients with blood cancers.

How similar studies have gone: Other studies have shown promising results with CAR-T cell therapy in hematological malignancies, indicating a potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with clinically diagnosed hematologic malignancies
* Patients treated with CAR-T cell therapy
* Signed the informed consent form

Where it's running

  • Institute of Hematology & Blood Diseases Hospital
    Tianjin, Tianjin Municipality, China
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.