Long-term outcomes for patients with lupus nephritis in China
High Quality Evidence of Guangzhou Lupus Nephritis Cohort (HOPE Cohort)
First Affiliated Hospital, Sun Yat-Sen University · NCT06682507
This study looks at how well people with lupus nephritis in China do over the long term to see if their kidney health and survival rates have improved since their diagnosis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 14 Years and up |
| Sex | All |
| Sponsor | First Affiliated Hospital, Sun Yat-Sen University (other) |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT06682507 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the long-term renal and patient survival outcomes of individuals diagnosed with lupus nephritis in China. It includes a cohort of patients who underwent renal biopsy for lupus nephritis, with data collected retrospectively from 1996 to 2016 and prospectively from 2017 onwards. The study will follow these patients to determine if their survival rates improve over time. By analyzing this data, the study seeks to provide insights into the management and prognosis of lupus nephritis.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 14 and older who have biopsy-proven lupus nephritis.
Not a fit: Patients under 14 years old or those who refuse to provide written consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of lupus nephritis outcomes, potentially leading to improved management strategies for patients.
How similar studies have performed: While observational studies on lupus nephritis exist, this specific cohort approach focusing on long-term outcomes in a Chinese population may provide novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients who had biopsy proven lupus nephritis in The First Affiliated Hospital of Sun Yat-sen University Exclusion Criteria: * less than 14 years old * refused to give written consent
Where this trial is running
Guangzhou, Guangdong
- The First Affiliated Hospital of Sun Yat-sen University — Guangzhou, Guangdong, China (RECRUITING)
Study contacts
- Principal investigator: Wei Chen, MD PHD — First Affiliated Hospital, Sun Yat-Sen University
- Study coordinator: Xi Xia, MD PHD
- Email: xiax29@mail.sysu.edu.cn
- Phone: +8618825134511
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Lupus Nephritis, lupus, lupus nephritis, outcomes, end stage kidney disease