Long-term outcomes for patients with lupus nephritis in China
Official title: High Quality Evidence of Guangzhou Lupus Nephritis Cohort (HOPE Cohort)
Run by First Affiliated Hospital, Sun Yat-Sen University · NCT06682507 · Data updated 2026-11-12
This study looks at how well people with lupus nephritis in China do over the long term to see if their kidney health and survival rates have improved since their diagnosis.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 14 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | First Affiliated Hospital, Sun Yat-Sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | January 1, 1996 |
| Main results expected | December 31, 2050 |
| Study ends | December 31, 2050 |
| Registry record updated | November 12, 2024 |
| Trial ID | NCT06682507 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 14 and older who have biopsy-proven lupus nephritis.
✕Probably not a fit
Patients under 14 years old or those who refuse to provide written consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the long-term renal and patient survival outcomes of individuals diagnosed with lupus nephritis in China. It includes a cohort of patients who underwent renal biopsy for lupus nephritis, with data collected retrospectively from 1996 to 2016 and prospectively from 2017 onwards. The study will follow these patients to determine if their survival rates improve over time. By analyzing this data, the study seeks to provide insights into the management and prognosis of lupus nephritis.
Why it matters
Potential benefit: If successful, this study could enhance understanding of lupus nephritis outcomes, potentially leading to improved management strategies for patients.
How similar studies have gone: While observational studies on lupus nephritis exist, this specific cohort approach focusing on long-term outcomes in a Chinese population may provide novel insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients who had biopsy proven lupus nephritis in The First Affiliated Hospital of Sun Yat-sen University Exclusion Criteria: * less than 14 years old * refused to give written consent
Where it's running
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The First Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China Recruiting
Study contacts
- Principal investigator: Wei Chen, MD PHD — First Affiliated Hospital, Sun Yat-Sen University
- Study coordinator: Xi Xia, MD PHD
- Email: xiax29@mail.sysu.edu.cn
- Phone: +8618825134511
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Lupus Nephritis Care Pathway
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This study tests whether adding empagliflozin to standard care improves kidney function in adults with active lupus nephritis.
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HB2198 for adults with moderate to severe lupus, including lupus nephritis and extra‑renal lupus
This trial will test whether two intravenous doses of HB2198 can safely reduce B cells and improve disease measures in adults with moderate to severe lupus, including lupus nephritis and extra‑renal lupus.
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HSK39297 tablets for lupus nephritis
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.