Long-term follow-up care for patients who received stem cell transplants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on the long-term evaluation and follow-up care of patients who have undergone allogeneic stem cell transplantation at the NIH Clinical Center. Participants, aged between 10 and 80 years, are monitored for their response to treatment, disease relapse, and late-occurring effects of the transplant. The study includes periodic physical examinations, blood tests, and bone marrow biopsies to assess complications such as graft-versus-leukemia and graft-versus-host disease. The aim is to collect data on long-term outcomes and complications associated with different transplant approaches.

Why it matters

Who can join: the full rules

* INCLUSION CRITERIA-TRANSPLANT RECIPIENTS:

Patients surviving three years or more from date of first stem cell transplant who have been treated.

-With an experimental allogeneic stem cell transplant on a NHLBI HB protocol

Or

-With a standard of care allogeneic stem cell transplant on an NHLBI protocol

Or

-Selectively, when the allogenic transplant was conducted outside the NIH, but the subject has a special condition of interest to the research team

Age greater than or equal to 7 years old and age less than or equal to 80

For adults: Ability to comprehend the investigational nature of the study and provide informed consent. For minors: Written informed consent from one parent or guardian and informed assent: The process will be explained to the minor on a level of complexity appropriate for their age and ability to comprehend.

EXCLUSION CRITERIA-STEM CELL TRANSPLANT RECIPIENTS:

None, all patients meeting the inclusion criteria will be eligible

Where it's running

• National Institutes of Health Clinical Center
  Bethesda, Maryland, United States Recruiting

Study contacts

• Principal investigator: Richard W Childs, M.D. — National Heart, Lung, and Blood Institute (NHLBI)
• Study coordinator: Bretagne C Cowling, R.N.
• Email: bretagne.cowling@nih.gov
• Phone: (301) 827-3479

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.