Link between artery stiffness and lung and other body features in ankylosing spondylitis
Investigation of the Relationship Between Arterial Stiffness and Pulmonary and Extrapulmonary Features in Patients With Ankylosing Spondylitis
We will try to see if stiffer arteries are linked with lung problems and other body features in adults aged 18–65 who have ankylosing spondylitis and are on stable medication.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 25 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | Kirsehir Ahi Evran Universitesi Academic / other |
| Locations | 1 site (Kırşehir) |
| Trial ID | NCT06739369 on ClinicalTrials.gov |
What this trial studies
This observational study will compare measures of arterial stiffness with pulmonary and other clinical features in people with ankylosing spondylitis. Eligible participants (age 18–65) must meet ASAS criteria and be on stable medication for at least three months; people with uncontrolled cardiopulmonary disease, recent surgery, malignancy, or pregnancy are excluded. Participants will attend the single site at Kirsehir Ahi Evran University for non-invasive vascular and pulmonary assessments and routine clinical examinations. The goal is to characterize patterns and relationships between vascular stiffness and disease manifestations rather than to test a treatment.
Who should consider this trial
Good fit: Adults 18–65 with ankylosing spondylitis by ASAS criteria who have been on stable medication for at least three months and can attend the study site are ideal candidates.
Not a fit: People with uncontrolled cardiopulmonary disease, recent surgery, active malignancy, pregnancy, or who cannot complete the required assessments are unlikely to benefit from participation.
Why it matters
Potential benefit: If a link is confirmed, the findings could help identify patients at higher cardiovascular or pulmonary risk and guide monitoring or preventive care.
How similar studies have performed: Previous research has reported increased arterial stiffness in people with ankylosing spondylitis, so this work builds on existing observational evidence rather than testing a new therapy.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of ankylosing spondylitis according to ASAS diagnostic criteria * Being aged 18-65 * Stable medication use for at least 3 months * Voluntary participation in the study Exclusion Criteria: * Having uncontrolled cardiopulmonary disease * Being pregnant * Having undergone recent surgery * Presence of malignancy * Failure to perform to assessments
Where this trial is running
Kırşehir
- Kirsehir Ahi Evran University — Kırşehir, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Merve Firat
- Email: mervefirat@ahievran.edu.tr
- Phone: +90 850 441 02 44
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.