Light therapy for improving symptoms in Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pivotal study investigates the effectiveness of a specialized light therapy device in enhancing both motor and non-motor functions in patients with Parkinson's disease, in conjunction with their current medical treatments. The study employs a six-month double-blind, randomized controlled design, with participants using the device at home for one hour each evening. Assessments will be conducted through virtual clinic visits at baseline, week 13, and week 26, focusing on quality of life and motor function through established scales. The primary outcome measure is the Parkinson's Disease Questionnaire-39 Summary Index, while secondary endpoints include the Movement Disorders Society-Unified Parkinson's Disease Rating Scale.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Diagnosis of Parkinson's disease as determined by the study PI, in keeping with the UK PD Society Brain Bank Criteria for the Diagnosis of PD

Responsiveness to dopaminergic medication, as judged by the rater, and have been using treatment for at least the past 1 year

Relatively good eyesight as attested to by participants (Corrective lenses of at least 20/60)

Stable levodopa and other anti-PD medications for at least 28 days prior to screening -

Exclusion Criteria:

Diagnosis of an atypical Parkinsonian syndrome

Significant OFF state or bothersome dyskinesias that in the judgment of the rater, would interfere with participation in the study.

An anticipated need for a change in dopamine replacement therapy, concomitant medications, OTC/supplements, or other alternative therapies during the participant's involvement in the investigation

History of previous light therapy use for PD

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Where it's running

• University of Rochester
  Rochester, New York, United States Recruiting

Study contacts

• Principal investigator: Ray Dorsey, MD — University of Rochester
• Study coordinator: Dan Adams
• Email: dan.adams@photopharmics.com
• Phone: 8014947804

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.