Left-atrial Fibrosis in Persistent Atrial Fibrillation and Its Comorbidities

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the relationship between comorbidities and left-atrial fibrosis in patients with persistent atrial fibrillation who are eligible for ablation. It aims to characterize how these comorbidities influence fibrosis and the likelihood of AF recurrence after ablation, and to determine how common these comorbidities are in this population. Participants will undergo screening for comorbid conditions, with data collection on fibrosis and recurrence outcomes. The study is conducted at University Hospital Augsburg under lead sponsor Christina Berr, MD, in Germany. Findings could improve understanding of fibrosis drivers and help tailor ablation decisions for patients with persistent AF.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* persistent atrial fibrillation, eligible for ablation
* BMI 19-40

Exclusion Criteria:

* valvular atrial fibrillation
* formerly ablation
* medication interfereing with measurements of atrial fibrosis
* known or treated comorbidities (OSAS, PA)

Where it's running

• University hospital Augsburg
  Augsburg, Bavaria, Germany Recruiting

Study contacts

• Study coordinator: Christina M Berr, MD
• Email: Christina.Berr@uk-augsburg.de
• Phone: +49821/400-165998

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.