Lefamulin Post-Market Surveillance in Community-Acquired Pneumonia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter, single-arm observational study collects real-world data on lefamulin use for community-acquired pneumonia in China. No new treatments are given as part of the study; patients are treated per routine clinical practice. Researchers will document outcomes, safety events, and patterns of lefamulin use across participating centers. The goal is to understand effectiveness and safety outside controlled trials and to inform future prescribing. The study is sponsored by Marubeni Pharmaceuticals with collaboration from China-Japan Friendship Hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Signed informed consent form
2. Clinical diagnosis of community-acquired pneumonia (CAP) by treating physicians
3. Currently receiving lefamulin treatment or prescribed and agreed to initiate lefamulin therapy as determined by the treating physician

Exclusion Criteria:

1. Patients with contraindications to lefamulin according to the approved prescribing information (e.g., known hypersensitivity to lefamulin or pleuromutilin class antibiotics)
2. Pulmonary infiltrates caused by non-infectious factors (e.g., pulmonary embolism, aspiration chemical pneumonitis, hypersensitivity pneumonitis, congestive heart failure, bronchial obstruction, lung cancer, cystic fibrosis)
3. Confirmed or suspected empyema via chest X-ray or CT examination
4. Participation in any other ongoing interventional clinical trial

Where it's running

• China-Japan Friendship Hospital
  Beijing, Beijing Municipality, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.