Clinical trial Recruiting at 1 site Early Phase 1 Interventional Ages 18 to 60

Ketamine to reduce shoulder pain after laparoscopic gastric sleeve

Official title: The Role of Intraoperative Ketamine Usage as Part of Anesthetic Management in Decreasing the Incidence of Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery

Run by King Abdullah University Hospital · NCT07429916 · Data updated 2026-11-12

This trial will try giving ketamine during surgery to see if it reduces shoulder pain after gastric sleeve operations for adults with obesity.

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Quick facts

PhaseEarly Phase 1
Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment50 (estimated)
SponsorKing Abdullah University Hospital
Academic / other
Locations1 site (Irbid)
StatusRecruiting
StartedJanuary 1, 2026
Main results expectedJune 30, 2026
Study endsAugust 30, 2026
Registry record updatedFebruary 24, 2026
Trial IDNCT07429916 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–60 undergoing laparoscopic sleeve gastrectomy with BMI >40 (or BMI >35 with obesity-related comorbidities) and ASA class 1–2 are the ideal candidates.

Probably not a fit

Patients outside the age or BMI criteria, with higher ASA scores, recent non-permitted analgesic use, a history of drug abuse, low cardiac ejection fraction, or those not having laparoscopic procedures are unlikely to match or benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This early-phase interventional study at King Abdullah University Hospital compares intraoperative ketamine to an anesthetic plan without ketamine for adults undergoing laparoscopic sleeve gastrectomy. Eligible participants are adults 18–60 years old with BMI >40 or BMI >35 with obesity-related comorbidities and ASA physical status 1–2. The study will record the incidence and intensity of post-laparoscopic shoulder pain and compare outcomes between the ketamine and non-ketamine groups. Key exclusions include recent analgesic use (within 24 hours except paracetamol), history of drug abuse, mental incapacity, and low ejection fraction.

Why it matters

Potential benefit: If successful, intraoperative ketamine could reduce how often and how severe shoulder pain is after laparoscopic gastric sleeve, improving patient comfort and recovery.

How similar studies have gone: Ketamine has been shown to reduce postoperative pain and opioid consumption in other surgical settings, but its specific effect on post-laparoscopic shoulder pain is less well studied.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients aged 18-60
* American society of anesthesiologist grade 1,2
* BMI \> 40
* BMI \> 35 with obesity-related comorbidities

Exclusion Criteria:

* mentally incapacitated
* patients received any type of analgesia 24hr preoperatively except paracetamol
* history of drug abuse
* patients with low ejection fraction

Where it's running

  • King Abdullah University Hospital
    Irbid, Jordan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.