Ketamine to reduce shoulder pain after laparoscopic gastric sleeve
Official title: The Role of Intraoperative Ketamine Usage as Part of Anesthetic Management in Decreasing the Incidence of Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery
Run by King Abdullah University Hospital · NCT07429916 · Data updated 2026-11-12
This trial will try giving ketamine during surgery to see if it reduces shoulder pain after gastric sleeve operations for adults with obesity.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | King Abdullah University Hospital Academic / other |
| Locations | 1 site (Irbid) |
| Status | Recruiting |
| Started | January 1, 2026 |
| Main results expected | June 30, 2026 |
| Study ends | August 30, 2026 |
| Registry record updated | February 24, 2026 |
| Trial ID | NCT07429916 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–60 undergoing laparoscopic sleeve gastrectomy with BMI >40 (or BMI >35 with obesity-related comorbidities) and ASA class 1–2 are the ideal candidates.
✕Probably not a fit
Patients outside the age or BMI criteria, with higher ASA scores, recent non-permitted analgesic use, a history of drug abuse, low cardiac ejection fraction, or those not having laparoscopic procedures are unlikely to match or benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This early-phase interventional study at King Abdullah University Hospital compares intraoperative ketamine to an anesthetic plan without ketamine for adults undergoing laparoscopic sleeve gastrectomy. Eligible participants are adults 18–60 years old with BMI >40 or BMI >35 with obesity-related comorbidities and ASA physical status 1–2. The study will record the incidence and intensity of post-laparoscopic shoulder pain and compare outcomes between the ketamine and non-ketamine groups. Key exclusions include recent analgesic use (within 24 hours except paracetamol), history of drug abuse, mental incapacity, and low ejection fraction.
Why it matters
Potential benefit: If successful, intraoperative ketamine could reduce how often and how severe shoulder pain is after laparoscopic gastric sleeve, improving patient comfort and recovery.
How similar studies have gone: Ketamine has been shown to reduce postoperative pain and opioid consumption in other surgical settings, but its specific effect on post-laparoscopic shoulder pain is less well studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients aged 18-60 * American society of anesthesiologist grade 1,2 * BMI \> 40 * BMI \> 35 with obesity-related comorbidities Exclusion Criteria: * mentally incapacitated * patients received any type of analgesia 24hr preoperatively except paracetamol * history of drug abuse * patients with low ejection fraction
Where it's running
-
King Abdullah University Hospital
Irbid, Jordan Recruiting
Study contacts
- Study coordinator: Anas Alrusan
- Email: amalrusan@just.edu.jo
- Phone: +962797015888
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.