Ketamine to reduce shoulder pain after laparoscopic gastric sleeve
The Role of Intraoperative Ketamine Usage as Part of Anesthetic Management in Decreasing the Incidence of Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery
This trial will try giving ketamine during surgery to see if it reduces shoulder pain after gastric sleeve operations for adults with obesity.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | King Abdullah University Hospital Academic / other |
| Locations | 1 site (Irbid) |
| Trial ID | NCT07429916 on ClinicalTrials.gov |
What this trial studies
This early-phase interventional study at King Abdullah University Hospital compares intraoperative ketamine to an anesthetic plan without ketamine for adults undergoing laparoscopic sleeve gastrectomy. Eligible participants are adults 18–60 years old with BMI >40 or BMI >35 with obesity-related comorbidities and ASA physical status 1–2. The study will record the incidence and intensity of post-laparoscopic shoulder pain and compare outcomes between the ketamine and non-ketamine groups. Key exclusions include recent analgesic use (within 24 hours except paracetamol), history of drug abuse, mental incapacity, and low ejection fraction.
Who should consider this trial
Good fit: Adults aged 18–60 undergoing laparoscopic sleeve gastrectomy with BMI >40 (or BMI >35 with obesity-related comorbidities) and ASA class 1–2 are the ideal candidates.
Not a fit: Patients outside the age or BMI criteria, with higher ASA scores, recent non-permitted analgesic use, a history of drug abuse, low cardiac ejection fraction, or those not having laparoscopic procedures are unlikely to match or benefit.
Why it matters
Potential benefit: If successful, intraoperative ketamine could reduce how often and how severe shoulder pain is after laparoscopic gastric sleeve, improving patient comfort and recovery.
How similar studies have performed: Ketamine has been shown to reduce postoperative pain and opioid consumption in other surgical settings, but its specific effect on post-laparoscopic shoulder pain is less well studied.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients aged 18-60 * American society of anesthesiologist grade 1,2 * BMI \> 40 * BMI \> 35 with obesity-related comorbidities Exclusion Criteria: * mentally incapacitated * patients received any type of analgesia 24hr preoperatively except paracetamol * history of drug abuse * patients with low ejection fraction
Where this trial is running
Irbid
- King Abdullah University Hospital — Irbid, Jordan (Recruiting)
Study contacts
- Study coordinator: Anas Alrusan
- Email: amalrusan@just.edu.jo
- Phone: +962797015888
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.