Isometric exercises and immediate pain sensitivity in chronic low back pain
Official title: Acute Effect of Isometric Excercise on Pain Sensitivity in Adults With Chronic Low Back Pain
Run by Taif University · NCT06963658 · Data updated 2026-11-12
This trial will try short isometric exercises to see if they quickly reduce pain sensitivity and current pain in adults with chronic low back pain.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | Taif University Academic / other |
| Locations | 1 site (Bisha, 'Asir Region) |
| Status | Recruiting |
| Started | August 1, 2025 |
| Main results expected | October 1, 2025 |
| Study ends | January 1, 2026 |
| Registry record updated | September 4, 2025 |
| Trial ID | NCT06963658 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults (18+) with non-specific chronic low back pain lasting more than 12 weeks who are able to perform isometric lower-limb/back exercises and have no medical contraindications to physical activity.
✕Probably not a fit
People with serious spinal pathology, neurological or spinal nerve compromise (including cauda equina), pregnancy or recent postpartum <1 year, uncontrolled diabetes, significant cardiovascular disease, major orthopedic or balance impairments, or other conditions preventing exercise are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, controlled study enrolls adults with non-specific chronic low back pain for a single two-hour visit. Participants are randomized to one of three conditions: repeated isometric wall squats, wall squats combined with a double-leg lower isometric hold, or quiet seated rest as a control. Researchers measure pressure pain threshold (PPT) and current low back pain intensity immediately before and right after the assigned intervention. The primary focus is the acute, immediate change in pain sensitivity following the intervention.
Why it matters
Potential benefit: If successful, the intervention could offer a quick, low-cost exercise option to reduce short-term pain sensitivity and temporarily lower pain in people with chronic low back pain.
How similar studies have gone: Prior small studies have reported short-term reductions in pain sensitivity after isometric exercise in some populations, but results are mixed and evidence specifically in chronic low back pain remains limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria : 1. participants aged ≥18 years or older 2. participant diagnosed with non-specific chronic lower back pain (\> 12 weeks) 3. Able to perform physical therapy excercise . Exclusion criteria : The study will exclude 1- pregnant women 2- lactating women for one or less than one year post-natal. 3- any certain medical conditions that could interfere with physical activity, including: * uncontrolled diabetes * cardiovascular problem * orthopedic impairments * balance problems. 4-serious spinal pathologies : * infection * fractures * tumors * inflammatory diseases like ankylosing spondylitis 5- neurological compromise, * spinal nerve compromise * cauda equina syndrome
Where it's running
-
King Abdullah Hospital in bisha
Bisha, 'Asir Region, Saudi Arabia Recruiting
Study contacts
- Study coordinator: Asma A Alqahtani, B.S.C
- Email: Alqahtaniasma61@gmail.com
- Phone: 966504435372
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.