Investigating Troponin T Fragmentation in Heart Injury
Troponin T Fragmentation in the Assessment of Myocardial Injury Study
This study looks at how Troponin T fragments in people who have had a heart attack or heart injury to see if it can help doctors better diagnose and manage these conditions.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Turku Academic / other |
| Locations | 2 sites (Turku, Southwest Finland and 1 other locations) |
| Trial ID | NCT04465591 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the fragmentation of Troponin T (TnT) in patients with acute myocardial infarction and myocardial injury. It will analyze the prevalence of TnT fragmentation across different patient cohorts, particularly in those with conditions that may elevate TnT levels, such as chronic kidney disease or following physical exercise. The study seeks to clarify the clinical significance of TnT fragmentation and its implications for diagnosing myocardial injury. By understanding these mechanisms, the research hopes to improve diagnostic accuracy and patient management in acute coronary syndromes.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who have had a Troponin T fragmentation sample collected and are experiencing acute myocardial infarction or myocardial injury.
Not a fit: Patients under 18 years of age will not be eligible for this study and therefore will not benefit from its findings.
Why it matters
Potential benefit: If successful, this study could enhance the diagnostic accuracy for myocardial injury, reducing unnecessary procedures and improving patient outcomes.
How similar studies have performed: While the fragmentation of Troponin T is a relatively novel area of investigation, previous studies have indicated potential benefits in understanding troponin dynamics, suggesting that this approach may yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Troponin T fragmentation sample collected from a recruited patient. Exclusion Criteria: * Age \<18
Where this trial is running
Turku, Southwest Finland and 1 other locations
- Turku University Hospital, Heart Center — Turku, Southwest Finland, Finland (Recruiting)
- University Hospital Zurich — Zurich, Switzerland (Enrolling_by_invitation)
Study contacts
- Principal investigator: Juhani K Airaksinen, MD, PhD — University of Turku
- Study coordinator: Juhani K Airaksinen, MD, PhD
- Email: juhani.airaksinen@tyks.fi
- Phone: +358 2 3131005
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.