Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating Troponin T Fragmentation in Heart Injury

Official title: Troponin T Fragmentation in the Assessment of Myocardial Injury Study

Run by University of Turku · NCT04465591 · Data updated 2026-11-12

This study looks at how Troponin T fragments in people who have had a heart attack or heart injury to see if it can help doctors better diagnose and manage these conditions.

More Myocardial Injury trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1500 (estimated)
SponsorUniversity of Turku
Academic / other
Locations2 sites (Turku, Southwest Finland and 1 other locations)
StatusRecruiting
StartedApril 2, 2020
Main results expectedDecember 30, 2028
Study endsDecember 31, 2028
Registry record updatedMay 8, 2026
Trial IDNCT04465591 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients who have had a Troponin T fragmentation sample collected and are experiencing acute myocardial infarction or myocardial injury.

Probably not a fit

Patients under 18 years of age will not be eligible for this study and therefore will not benefit from its findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the fragmentation of Troponin T (TnT) in patients with acute myocardial infarction and myocardial injury. It will analyze the prevalence of TnT fragmentation across different patient cohorts, particularly in those with conditions that may elevate TnT levels, such as chronic kidney disease or following physical exercise. The study seeks to clarify the clinical significance of TnT fragmentation and its implications for diagnosing myocardial injury. By understanding these mechanisms, the research hopes to improve diagnostic accuracy and patient management in acute coronary syndromes.

Why it matters

Potential benefit: If successful, this study could enhance the diagnostic accuracy for myocardial injury, reducing unnecessary procedures and improving patient outcomes.

How similar studies have gone: While the fragmentation of Troponin T is a relatively novel area of investigation, previous studies have indicated potential benefits in understanding troponin dynamics, suggesting that this approach may yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Troponin T fragmentation sample collected from a recruited patient.

Exclusion Criteria:

* Age \<18

Where it's running

  • Turku University Hospital, Heart Center
    Turku, Southwest Finland, Finland
    Recruiting
  • University Hospital Zurich
    Zurich, Switzerland
    Enrolling by invitation

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.