Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating the role of sTREM in outcomes after thrombectomy for stroke

Official title: Soluble Soluble Triggering Receptors Expressed on Myeloid Cells (sTREM) Predict Outcomes in Stroke Patients Receiving Endovascular Thrombectomy

Run by The Affiliated Hospital of Xuzhou Medical University · NCT06545591 · Data updated 2026-11-12

This study is trying to see if certain proteins in the blood can help predict how well people recover after a procedure to remove a blood clot from their brain during a stroke.

More Acute Ischemic Stroke trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorThe Affiliated Hospital of Xuzhou Medical University
Academic / other
Locations1 site (Xuzhou, Jiangsu)
StatusRecruiting
StartedJuly 1, 2024
Main results expectedDecember 31, 2027
Study endsDecember 31, 2027
Registry record updatedAugust 9, 2024
Trial IDNCT06545591 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old with acute large vessel occlusion who are scheduled to receive endovascular treatment within 24 hours of symptom onset.

Probably not a fit

Patients who are unable to provide blood samples or those who refuse informed consent may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the prognostic significance of soluble triggering receptors expressed on myeloid cells (sTREM1 and sTREM2) in patients with acute ischemic stroke who undergo endovascular thrombectomy (EVT). By analyzing blood samples taken before and after the procedure, the study seeks to establish a correlation between sTREM levels and functional outcomes at three months post-stroke. The research will also include non-stroke controls and patients who did not receive EVT to provide a comprehensive understanding of sTREM's role in stroke recovery.

Why it matters

Potential benefit: If successful, this study could help identify biomarkers that predict recovery outcomes for stroke patients undergoing thrombectomy.

How similar studies have gone: While the role of sTREM in stroke outcomes is being explored, this specific approach appears to be novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients \> 18 years old.
* Patients with acute large vessel occlusion within 24 hours of onset who will receive endovascular treatment.

Exclusion Criteria:

* Impossibility of getting a blood sample.
* Impossibility of performing the test (Invalid results).
* Refusal to provide the informed consent by the patient/relative.

Where it's running

  • Department of Neurology
    Xuzhou, Jiangsu, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.