Investigating the prevalence of metabolic associated fatty liver disease in patients with type 2 diabetes in Jiangsu Province, China
Official title: Prevalence of Metabolic Associated Fatty Liver Disease in Patients With Type 2 Diabetes in Jiangsu Province of China: a Prospective, Multicenter, Real-world Study
Run by Wuxi Hisky Medical Technology Co Ltd · NCT05597709 · Data updated 2026-11-12
This study looks at how common fatty liver disease is in people with type 2 diabetes in Jiangsu Province, China, and how it relates to their insulin levels.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2900 (estimated) |
| Sponsor | Wuxi Hisky Medical Technology Co Ltd Industry-sponsored |
| Locations | 1 site (Nanjing, Jiangsu) |
| Status | Recruiting |
| Started | July 1, 2022 |
| Main results expected | June 1, 2023 |
| Study ends | June 1, 2027 |
| Registry record updated | October 28, 2022 |
| Trial ID | NCT05597709 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults diagnosed with type 2 diabetes mellitus who meet the inclusion criteria and are willing to participate.
✕Probably not a fit
Patients with other types of diabetes or those unable to attend regular follow-ups may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the prevalence and clinical characteristics of metabolic associated fatty liver disease (MAFLD) in patients diagnosed with type 2 diabetes mellitus (T2DM) in Jiangsu Province, China. It will utilize ultrasound attenuation parameters to non-invasively evaluate liver fat content and its correlation with insulin resistance. The study will involve measuring fasting blood glucose and insulin levels to better understand the relationship between T2DM and MAFLD. By identifying these correlations, the study seeks to enhance the understanding of how these conditions interact and affect patient outcomes.
Why it matters
Potential benefit: If successful, this study could lead to improved screening and management strategies for patients with type 2 diabetes and metabolic associated fatty liver disease.
How similar studies have gone: While there is limited data on the specific correlation between ultrasound attenuation parameters and insulin resistance in this context, similar studies have shown promising results in understanding the relationship between diabetes and fatty liver disease.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosed as T2DM according to the Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes * UAP were measured based on iLivTouch * Willing to attend this study and able to provide the written informed consent. Exclusion Criteria: * Other types of diabetes * Patients unable to receive regular follow-up
Where it's running
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Zhongda Hospital, Medical School, Southeast University
Nanjing, Jiangsu, China Recruiting
Study contacts
- Principal investigator: Ling Li, Professor — Zhongda Hospital
- Study coordinator: Ling Li, Professor
- Email: lingli2022@hotmail.com
- Phone: +8613951606816
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Glucagon resistance in MASLD and type 2 diabetes
This will see if people with type 2 diabetes, with or without MASLD, respond differently to glucagon in liver fat oxidation and VLDL-triglyceride secretion.
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Rifaximin treatment for metabolic-associated fatty liver disease
This trial tests whether taking oral rifaximin for 24 weeks helps adults with metabolic-associated fatty liver disease (MAFLD) and is safe.
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New MRI methods to measure metabolism and predict outcomes in metabolic-associated fatty liver disease
This project tests whether new MRI techniques can measure body metabolism and help predict disease status and prognosis for people with metabolic-associated fatty liver disease.
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Non-invasive blood and imaging tests for metabolic liver disease
This project tests whether blood tests and imaging scans can diagnose and stage metabolic-associated steatohepatitis (MASH) and liver fibrosis in adults with metabolic risk factors.
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Effects of a Low Valine Diet on Weight and Metabolism
This study is testing if meal replacements with less valine can help overweight and obese people lose weight and improve their metabolism compared to regular meal replacements.
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Understanding Metabolic Associated Fatty Liver Disease in China
This study is trying to learn more about metabolic liver disease in China by collecting health information and samples from patients to find markers that could help predict how the disease affects them.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.