Investigating the link between obstructive sleep apnea and pulmonary hypertension

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the prevalence, phenotypes, and predictors of obstructive sleep apnea (OSA) in patients diagnosed with pulmonary hypertension. Adult participants will undergo an overnight cardiorespiratory study using a Level III portable device to assess their sleep patterns and related physiological parameters. The study will categorize patients into OSA and non-OSA groups based on their apnea-hypopnea index (AHI) and collect data on hypoxemic parameters and baseline clinical characteristics. The goal is to determine the impact of OSA on clinical outcomes in this patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged ≥18 years old
* Diagnosed with pulmonary hypertension by right heart catheterization

Exclusion Criteria:

* Pregnancy
* Central sleep apnea
* Previous treatment for sleep-disordered breathing
* Unavailable or incomplete sleep data
* Requiring nocturnal oxygen supplementation

Where it's running

• Center for Respiratory and Pulmonary Vascular Diseases, Fuwai hospital, CAMS & PUMC
  Beijing, China Recruiting

Study contacts

• Principal investigator: Zhihong Liu — Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
• Study coordinator: Zhihong Liu, M.D., Ph.D
• Email: zhihongliufuwai@163.com
• Phone: +861088396590

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using a sleep medication to help people with obstructive sleep apnea tolerate CPAP

  The trial will test whether giving the sleep medicine eszopiclone to people with obstructive sleep apnea (AHI ≥10/hour) helps them stick with CPAP and improves thinking skills.

  Recruiting Phase 3 Yale University · North Haven, Connecticut · NCT07332442

• Daytime versus overnight titration for hypoglossal nerve stimulation

  We will test whether a daytime sleep test works as well as an overnight sleep test to fine-tune hypoglossal nerve stimulation for people with moderate to severe obstructive sleep apnea.

  Recruiting University Hospital, Antwerp · Edegem, Antwerp · NCT06559956

• Registry for patients with obstructive sleep apnea treated with hypoglossal nerve stimulation

  This study is collecting information from patients with moderate to severe obstructive sleep apnea who are using a new device called Inspire to see how well it works and how it helps them over five years.

  Recruiting at 2 sites University Hospital, Antwerp · Edegem, Antwerp and 1 other locations · NCT06332404

• Multimodal Deep Learning to Predict Sleep Apnea Severity from SpO2 and Ballistocardiography

  Researchers are testing a smart-mattress-based method that uses SpO2 and ballistocardiography data to predict sleep apnea severity in adults undergoing overnight sleep study.

  Recruiting Fu Jen Catholic University · New Taipei City, New Taipei City · NCT07923825

• Nightly wearable monitoring with at-home submental electrical stimulation for sleep apnea

  This pilot test checks whether wearing a ring sensor at night and doing a 4-week at-home submental electrical stimulation is feasible for adults with obstructive sleep apnea and looks at changes in sleep metrics.

  Recruiting E-DA Hospital · Kaohsiung City · NCT07921329

• Levosimendan to see if it helps the heart after PEA in CTEPH

  This small randomized trial tests whether giving levosimendan around surgery helps reduce pulmonary artery pressure and support right heart function after pulmonary endarterectomy for CTEPH.

  Recruiting Meshalkin Research Institute of Pathology of Circulation · Novosibirsk · NCT07914933

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.