Investigating risk factors for liver inflammation and fibrosis in patients with chronic hepatitis B and non-alcoholic fatty liver disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the risk factors associated with hepatic inflammation and fibrosis in patients suffering from chronic hepatitis B (CHB) and non-alcoholic fatty liver disease (NAFLD). By utilizing a multicenter approach, the study will establish diagnostic models to better understand the progression of liver-related complications such as cirrhosis and liver cancer. The research will focus on identifying key indicators that predict the risk of severe liver conditions in this patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1.18 years or older 2. Positive hepatitis B surface antigen (HBsAg) for at least 6 months and without other viral co-infection at baseline 2.NAFLD diagnosed by imaging liver biopsy, and/or blood testing/predictive indices

Exclusion Criteria:

1. Other chronic liver diseases, such as alcoholic liver disease, other viral hepatitis, drug-induced liver injury;
2. HCC or other malignancies before liver biopsy;

Where it's running

• Nanjing Drum Tower Hospital
  Nanjing, China Recruiting

Study contacts

• Study coordinator: Jie Li, M.D., Ph.D
• Email: lijier@sina.com
• Phone: 15863787910

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.