Investigating non-invasive brain stimulation for drug-resistant epilepsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective study explores the effects of temporal interference (TI) on deep brain stimulation in patients aged 14-60 with drug-resistant epilepsy. By utilizing stereoelectroencephalography (SEEG), the study aims to analyze the electrophysiological mechanisms of TI, which generates focused stimulation in targeted brain areas without invasive procedures. Clinical, imaging, and electrophysiological data will be collected and analyzed to enhance understanding of TI's impact on brain function and its potential as a treatment alternative.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of drug-resistant epilepsy;
* No severe systemic diseases;
* Implantation of stereotactic electrodes;
* Agreement to participate in this study and signs the informed consent form.

Exclusion Criteria:

* Hematoma at the scalp electrode site or fluid accumulation under the electrode after intracranial electrode placement.

Where it's running

• Xuanwu Hospital,Capital Medical University
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Liankun Ren, MD — Xuanwu Hospital, Beijing
• Study coordinator: Liankun Ren, MD
• Email: renlk2022@outlook.com
• Phone: +86 13681576621

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant Epilepsy

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• iVEAcare Neuromodulation System for drug‑resistant epilepsy: a feasibility look

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• Real-world use of the OneRF Ablation System for epilepsy

  This registry collects real-world outcomes and device performance from patients with drug-resistant epilepsy who are treated with SEEG-guided RF ablation using the OneRF system.

  Recruiting at 3 sites NeuroOne Medical Technologies Corporation · Miami, Florida and 2 other locations · NCT07546253

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.