Investigating new cardiac biomarkers for diagnosing acute coronary syndrome
Biomarkers in Acute Cardiac Care
This study is testing new blood markers to see if they can help doctors better diagnose acute coronary syndrome in patients who might be having a heart attack.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universitätsklinikum Hamburg-Eppendorf Academic / other |
| Locations | 1 site (Hamburg) |
| Trial ID | NCT02355457 on ClinicalTrials.gov |
What this trial studies
This study aims to identify and evaluate new cardiac biomarkers and algorithms to improve the diagnosis of acute coronary syndrome (ACS) in patients suspected of having an acute myocardial infarction. It will assess various risk factors, including clinical, gender-specific, psychosocial, and lifestyle factors, alongside genetic variability and protein patterns. The study will also estimate the incidence of ACS in patients with recent chest pain and explore the impact of socioeconomic factors on cardiovascular risk. Participants will be followed during their hospital stay and through telephone follow-ups at specified intervals.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 18 and older who exhibit symptoms suggestive of acute myocardial infarction and can provide informed consent.
Not a fit: Patients who do not speak or understand German may not benefit from this study due to language barriers.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and timely diagnoses of acute coronary syndrome, potentially improving patient outcomes.
How similar studies have performed: Other studies have shown promise in using biomarkers for diagnosing acute coronary syndrome, but this approach includes novel elements that may enhance existing methodologies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Symptoms suggestive of acute myocardial infarction * Ability to provide written informed consent in accordance with Good epidemiological Practice and local legislation * Individuals at least 18 years old Exclusion Criteria: \- Insufficient knowledge of the German language (able to understand and write the German language)
Where this trial is running
Hamburg
- Department of Cardiology, University Heart Center Hamburg — Hamburg, Germany (Recruiting)
Study contacts
- Principal investigator: Johannes Neumann, MD — Uhz
- Study coordinator: Johannes T Neumann, MD
- Email: j.neumann@uke.de
- Phone: 0049407410
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.