Investigating muscle weakness in breathing among patients with systemic sclerosis
Investigation of Respiratory Muscle Sarcopenia in Patients With Systemic Sclerosis
This study is trying to see how muscle weakness affects breathing in people with systemic sclerosis by looking at their strength and physical performance.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 85 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Selcuk University Academic / other |
| Locations | 1 site (Konya, Selcuklu) |
| Trial ID | NCT06598982 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the prevalence of respiratory muscle sarcopenia in individuals diagnosed with systemic sclerosis. It evaluates participants' body composition, hand grip strength, and physical performance through various tests, including the 5 repetition sit-and-stand test and the Timed up-and-go test. The study also measures respiratory muscle strength to understand the impact of sarcopenia on respiratory function in these patients. By utilizing established guidelines for diagnosing sarcopenia, the study seeks to provide insights into the relationship between systemic sclerosis and respiratory muscle health.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18-75 who have been diagnosed with systemic sclerosis and are clinically stable.
Not a fit: Patients with neurological or musculoskeletal issues that affect muscle strength measurement or those with severe infections or other rheumatologic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of respiratory complications in systemic sclerosis, leading to better management strategies for affected patients.
How similar studies have performed: While the specific focus on respiratory muscle sarcopenia in systemic sclerosis may be novel, related studies on sarcopenia and muscle strength have shown promising results in other populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being between the ages of 18-75 * 2013 To be diagnosed with systemic sclerosis according to ACR/EULAR classification criteria * Being clinically stable * Ability to adapt to tests (visual, cognitive, cooperative) Exclusion Criteria: * Those with neurological and/or musculoskeletal problems that may affect the work * Presence of severe joint contracture or painful ulcers that may affect muscle strength measurement and walking * Presence of severe infection or sepsis * Being diagnosed with a known additional rheumatologic disease * Any stage of cancer * Pregnant or breastfeeding
Where this trial is running
Konya, Selcuklu
- Selcuk University — Konya, Selcuklu, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Yasemin GEDIKLI, MSc in PT
- Email: yasemin.gedikli@selcuk.edu.tr
- Phone: 5067246602
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.