Investigating melatonin phase delay in children with idiopathic scoliosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the prevalence and clinical significance of melatonin phase delay in children who have newly developed and progressive idiopathic scoliosis. It focuses on understanding the potential link between melatonin deficiency and the development of scoliosis, as previous research has suggested that melatonin may play a role in the condition's etiology. The study will involve collecting saliva samples for melatonin testing and assessing scoliosis through scoliometer or X-ray evaluations. Participants will be skeletally immature children aged 6 to 15 who can complete specific questionnaires.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Collect saliva according to standards and complete melatonin testing

  * Complete scoliometer or X-ray assess scoliosis
  * Skeletally immature (Risser Sign 0-3)
  * Age between 6 and 15
  * Patients can understand and complete the MEQ-5, PSQ, and PSQI Questionnaire at baseline and follow-up visits
  * Informed Consent Form signed by subject or the guardian

Exclusion Criteria:

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Where it's running

• The Second Affiliated Hospital of Wenzhou Medical University
  Wenzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: Xiangyang Wang, MD
• Email: Xiangyangwang@wmu.edu.com
• Phone: 86-13506663458

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.