Investigating long-term effects of COVID-19 recovery

LOng COvid COmorbidities: Evaluation of Endocrine, Metabolic, Neuropsychiatric, Muscle, Cardiovascular, Pulmonary and Dermatologic Functions

Observational Federico II University · NCT05293366

This study is trying to see what long-term health problems people might have after recovering from COVID-19.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorFederico II University Academic / other
Locations1 site (Naples)
Trial IDNCT05293366 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the long-term sequelae of SARS-CoV-2 infection in patients who have recovered from COVID-19. It focuses on assessing various potential complications, including endocrine, metabolic, neuropsychiatric, muscular, pulmonary, cardiovascular, and dermatological issues. Patients will be evaluated at baseline upon discharge and again after 3 to 12 months to determine the prevalence and types of these complications. The findings could significantly enhance therapeutic management and long-term follow-up for these patients.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years who have recovered from SARS-CoV-2 infection and can understand the study procedures.

Not a fit: Patients with psychological, psychiatric, or other medical conditions that impair their understanding of the study may not benefit.

Why it matters

Potential benefit: If successful, this study could lead to improved management strategies for patients recovering from COVID-19 by identifying and addressing long-term health complications.

How similar studies have performed: While there is ongoing research into COVID-19 sequelae, this specific focus on a comprehensive range of long-term complications in recovered patients is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients of both sexes recovered from SARS-CoV-2 infection (two negative nasopharyngeal swabs, negative IgM and positive anti SARS-CoV-2 IgG);
* Aged over 18 years of age;
* Ability to understand protocol procedures

Exclusion Criteria:

* Any psychological/psychiatric/other medical conditions compromising the understanding of the nature and purpose of the study, and of its possible consequences
* uncooperative attitude of the patient

Where this trial is running

Naples

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Long Covid-19Endocrine ComplicationsMetabolic ComplicationsNeuropsychiatric ComplicationsMuscular ComplicationsCardiovascular ComplicationsPulmonary ComplicationsDermatologic Complications
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.