Investigating neurological complications of long COVID in children and adolescents

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on understanding the neurological effects of long COVID-19 in children and adolescents aged 6 to 16 years. It employs neuropsychological assessments, electroencephalography (EEG), and magnetic resonance imaging (MRI) to evaluate the persistence or emergence of neurological symptoms following SARS-CoV-2 infection. The goal is to identify and characterize the neurological complications associated with long COVID in this age group. By gathering data on symptoms such as fatigue, cognitive dysfunction, and mood disorders, the study aims to provide insights into the long-term impacts of COVID-19 on young patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 6 years and 16 years and 11 months
* Symptomatology compatible with long neurological COVID, specifically: persistence or appearance of new neurological signs/symptoms (e.g. fatigue, headache, sleep disturbance, cognitive dysfunction, memory difficulties, emotional or mood disorders, vertigo cognitive dysfunction, memory difficulties, emotional or mood disorders, dizziness, dysautonomia, movement disorders movement disorders, ataxia, tremor, epilepsy, muscle weakness, myalgia, hyposmia, hypogeusia hearing loss or tinnitus and/or sensorimotor deficits such as hypoesthesia, dysesthesia) after three months after established SARS-CoV-2 infection, as well as persistence of these symptoms for at least two months, in the absence of a clear aetiology.
* Signature of the appropriate Informed Consent by caregiver(s) and patient(s)

Exclusion Criteria:

* Poor knowledge of the Italian language or other limitation of verbal communication that compromises the subject's ability to perform neuropsychological tests
* Need for sedation to perform brain MRI 7 Tesla
* Neurological or neuropsychiatric disorder diagnosed prior to COVID-19 diagnosis
* Caregiver's failure to sign consent

Where it's running

• Azienda Ospedaliera Universitaria Pisana
  Pisa, Pi, Italy Recruiting

Study contacts

• Study coordinator: Alessandro Orsini, Dirigente medico
• Email: neuropediatriapisa@gmail.com
• Phone: +050 995995

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.