Investigating long-term effects of COVID-19 on male and female reproductive health
LOng COvid COmorbidities: Evaluation of Andrological, Reproductive and Sexual Functions in Patients Recovered From COVID-19
This study is trying to see how COVID-19 affects the reproductive health and sexual function of men and women after they recover from the virus.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Federico II University Academic / other |
| Locations | 1 site (Naples, Italy) |
| Trial ID | NCT05379556 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the long-term effects of COVID-19 on andrological, reproductive, and sexual functions in patients who have recovered from the virus. It will assess potential damage to the hypothalamic-pituitary-testicular hormonal axis in male patients, as well as the prevalence of olfactory dysfunction in both male and female patients. The study will involve detailed assessments of sexual function, reproductive health, and olfactory capabilities, correlating these findings with the severity of the initial COVID-19 infection. Participants will be evaluated at discharge from the infectious phase and monitored for any lasting complications.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who have recovered from COVID-19 and can understand the study's procedures.
Not a fit: Patients with psychological or psychiatric conditions that impair their understanding of the study may not benefit from participation.
Why it matters
Potential benefit: If successful, this study could provide insights into the long-term reproductive health challenges faced by COVID-19 survivors, leading to better management and treatment options.
How similar studies have performed: While there is a growing body of research on COVID-19's acute effects, studies specifically addressing long-term reproductive and sexual health outcomes are still emerging and may be novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients of both sexes recovered from SARS-CoV-2 infection (two negative nasopharyngeal swabs, negative IgM and positive anti SARS-CoV-2 IgG); * Aged over 18 years of age; * Ability to understand protocol procedures Exclusion Criteria: * Any psychological/psychiatric/other medical conditions compromising the understanding of the nature and purpose of the study, and of its possible consequences * Uncooperative attitude of the patient
Where this trial is running
Naples, Italy
- Federico II University of Naples — Naples, Italy, Italy (Recruiting)
Study contacts
- Principal investigator: Rosario Pivonello, Prof. — Federico II University
- Study coordinator: Rosario Pivonello, Prof.
- Email: rosario.pivonello@unina.it
- Phone: 3317328474
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.