Investigating kidney function during dialysis in ICU patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines the physiological changes in the kidneys of ICU patients suffering from acute kidney injury (AKI) when starting continuous renal replacement therapy (CRRT) at different blood pressure levels. By enrolling 20 patients, the research aims to determine the optimal blood pressure for kidney function during dialysis using a retrograde renal vein thermodilution technique. Additionally, the study will validate this invasive method with contrast-enhanced ultrasound of the kidneys to provide a comprehensive understanding of renal physiology during treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

AKI, according to KDIGO, stage 2 or 3 but with preserved urine production. Treated in the ICU at Sahlgrenska University Hospital Written, signed informed consent Male and female subjects ≥18 years

Exclusion Criteria:

Emergency need for dialysis Allergy to contrast media (used for CEUS)

Where it's running

• Sahlgrenska University Hospital
  Gothenburg, Sweden Recruiting

Study contacts

• Principal investigator: Kristina Svennerholm, MD PhD
• Study coordinator: Kristina Svennerholm, MD PhD
• Email: kristina.svennerholm@vgregion.se
• Phone: +46313429336

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.