Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating inflammation's role in vascular disease

Official title: The Role of Inflammation in Vascular Disease (Inflammationens Roll i kärlsjukdom)

Run by Göteborg University · NCT03732612 · Data updated 2026-11-12

This study is trying to see how low-grade inflammation affects heart and blood vessel problems in patients having vascular surgeries compared to those having other types of surgeries.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment170 (estimated)
SponsorGöteborg University
Academic / other
Locations1 site (Gothenburg, Vastragotaland)
StatusRecruiting
StartedSeptember 2, 2019
Main results expectedFebruary 1, 2026
Study endsFebruary 1, 2027
Registry record updatedMay 6, 2025
Trial IDNCT03732612 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients scheduled for vascular surgery related to peripheral arterial diseases or atherosclerosis.

Probably not a fit

Patients under 18 years of age or those participating in drug-related studies may not benefit from this research.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the connection between systemic low-grade inflammation and various cardiovascular conditions, including vascular dysfunction and atherosclerosis. Patients undergoing vascular surgeries will have excised tissue collected for research purposes, which will be cultured to assess the effects of therapeutic agents on inflammation. The study will also include control patients who have undergone unrelated surgeries to compare the findings. The goal is to better understand how inflammation contributes to vascular diseases.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic strategies for managing vascular diseases and improving patient outcomes.

How similar studies have gone: While the role of inflammation in cardiovascular disease has been studied, this specific approach of utilizing excised vascular tissue for research is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient is planned to undergo vascular surgery.
* Signed informed consent has been obtained from the patient.

Exclusion Criteria:

* Patient has difficulty to understand information.
* Patients under 18 years of age.
* Patients participating in any drug-related study.

Where it's running

  • University of Gothenburg
    Gothenburg, Vastragotaland, Sweden
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.