Investigating immune and placental cell interactions in pregnancy complications

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on understanding how different immune cells and placental cells interact and contribute to pregnancy complications such as preeclampsia and gestational diabetes. It aims to explore the mechanisms by which uteroplacental syndrome may lead to maternal health issues, particularly through the induction of endothelial dysfunction and cardiovascular damage. The study will involve healthy pregnant women and those diagnosed with specific pregnancy-related conditions, collecting data to better understand these complex interactions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* healthy pregnant women after giving informed consent
* pregnant with diagnosis of preeclampsia, gestational hypertension or gestational diabetes

Exclusion Criteria:

* infections
* alcohol and drug abuse
* manifest and chronic diseases

Where it's running

• Experimental and Clinical Research Center (ECRC)
  Berlin, Germany Recruiting

Study contacts

• Study coordinator: Florian Herse, PhD
• Email: florian.herse@charite.de
• Phone: +49 30 450 540 434

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Evaluating new ultrasound techniques for assessing placental health

  This study is testing new ultrasound techniques to see if they can help tell the difference between healthy pregnancies and those with fetal growth issues.

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• Examining how aspirin metabolism relates to metabolic dysfunction in pregnant individuals at risk of preeclampsia

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• Improving oral health during pregnancy to prevent complications

  This study tests if treating gum disease in pregnant women can help their babies grow better and lower the chances of early delivery.

  Recruiting at 3 sites University Hospital Bispebjerg and Frederiksberg · Holbæk, Holbaek and 2 other locations · NCT06110143

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.