Investigating how maternal health affects childhood obesity and cardiometabolic disorders
Official title: Prenatal Programming of Childhood Obesity and Cardio Metabolic Disorders - Role of Maternal Obesity, Pregnancy Complications, and Maternal-fetal Metabolome
Run by Helsinki University Central Hospital · NCT05223530 · Data updated 2026-11-12
This study looks at how a mother's health during pregnancy affects her child's risk of obesity and heart problems as they grow up.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 11 Years to 55 Years |
| Sex | All |
| Enrollment | 750 (estimated) |
| Sponsor | Helsinki University Central Hospital Academic / other |
| Locations | 1 site (Helsinki) |
| Status | Recruiting |
| Started | February 25, 2022 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | September 24, 2026 |
| Trial ID | NCT05223530 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include mothers who participated in the original PREDO or RADIEL studies during their pregnancy and their children aged 11-17 years.
✕Probably not a fit
Patients who did not participate in the PREDO or RADIEL studies during pregnancy will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study follows mothers and their children from two Finnish pregnancy cohorts to explore the links between maternal health conditions, such as obesity and gestational diabetes, and the subsequent health outcomes in their children. The study will assess various factors, including body composition and cardiovascular health, in children aged 11-17 years. Data will be collected through detailed health assessments and metabolomic analyses to understand the impact of maternal conditions on child health outcomes.
Why it matters
Potential benefit: If successful, this study could provide insights into preventing childhood obesity and related cardiometabolic disorders by addressing maternal health during pregnancy.
How similar studies have gone: Other studies have shown success in linking maternal health to childhood obesity, making this approach both relevant and supported by existing research.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * all mothers participated originally in the PREDO or the RADIEL studies during pregnancy and with delivery during this index pregnancy Exclusion Criteria: \-
Where it's running
-
Saila Koivusalo
Helsinki, Finland Recruiting
Study contacts
- Study coordinator: Saila B Koivusalo, prof
- Email: saila.koivusalo@hus.fi
- Phone: +358407250620
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.