Investigating how caspofungin works in children with severe infections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the pharmacokinetics and pharmacodynamics of caspofungin, an antifungal medication, in children suffering from severe infections with specific conditions such as liver insufficiency, hypoproteinemia, ECMO treatment, or sepsis. The study will involve blood sampling at various time points after administration to analyze how the drug is metabolized in these unique patient populations. The goal is to determine whether the current dosing recommendations are effective in achieving optimal drug levels in these children.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children receiving caspofungin in pediatric intensive care unit

Exclusion Criteria:

* No Informed Consent signed Participate in other clinical trials

Where it's running

• Children's Hospital of Fudan University
  Shanghai, Shanghai Municipality, China Recruiting
• Children's Hospital of Fudan University
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Principal investigator: Guoping Lu, doctor — Children's Hospital of Fudan University
• Study coordinator: Yixue Wang, doctor
• Email: yixuewang08@aliyun.com
• Phone: 8613524669352

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.