Investigating health consequences in azoospermia patients
Official title: Prospective Cohort Study for Azoospermia Patients in Clinical Reproductive Medicine Management System/Electronic Medical Record Cohort Database (CCRM/EMRCD)
Run by The First Affiliated Hospital of Zhengzhou University · NCT03991663 · Data updated 2026-11-12
This study looks at the health effects of azoospermia in men to see how it impacts their overall well-being and fertility.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | Men only |
| Enrollment | 10000 (estimated) |
| Sponsor | The First Affiliated Hospital of Zhengzhou University Academic / other |
| Locations | 1 site (Zhengzhou, Henan) |
| Status | Recruiting |
| Started | January 1, 2010 |
| Main results expected | December 31, 2050 |
| Study ends | December 31, 2050 |
| Registry record updated | June 19, 2019 |
| Trial ID | NCT03991663 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are men diagnosed with azoospermia, confirmed by multiple semen evaluations showing no sperm.
✕Probably not a fit
Patients with azoospermia who do not meet the inclusion criteria or those with other underlying conditions affecting fertility may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on azoospermia, a condition affecting male fertility, by examining the short- and long-term health outcomes of affected individuals. Conducted at the Reproductive Medical Center of the First Affiliated Hospital of Zhengzhou University, the study utilizes a comprehensive database that includes biological samples, questionnaires, and health data from participants. The aim is to gather evidence that can inform prognosis and management of azoospermia, which is a significant factor in infertility for many couples.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the health implications of azoospermia, potentially leading to improved management strategies for affected patients.
How similar studies have gone: While there have been studies on male infertility, this specific focus on azoospermia and its health consequences is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * at least three semen evaluations performed on separate occasions, when the seminal specimen after centrifugation showed no sperm under the microscope and was then diagnosed according to several clinical parameters； Exclusion Criteria: \-
Where it's running
-
Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China Recruiting
Study contacts
- Study coordinator: Lanlan Fang, M.D.
- Email: fanglly@163.com
- Phone: 13673355291
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Investigating health consequences in women with primary ovarian insufficiency
This study is trying to learn more about the health effects of premature ovarian insufficiency in women by collecting health information and samples to see how it impacts their lives.
-
PDT plus radioactive biliary stent for unresectable extrahepatic cholangiocarcinoma
This study tests whether combining photodynamic therapy with a self-expandable radioactive stent can help patients with unresectable extrahepatic cholangiocarcinoma stay cancer-free longer and keep their bile ducts open.
-
Hepatic arterial infusion chemotherapy vs capecitabine after surgery for biliary tract cancers
This study tests whether hepatic arterial infusion chemotherapy after surgery helps patients with biliary tract cancers more than capecitabine.
-
How long to fast after esophageal variceal ligation in cirrhosis
This trial tests whether starting oral intake 6 hours after EVL is safer and as effective as waiting 24 or 48 hours in adults with cirrhosis and esophageal varices.
-
A combination therapy for advanced second-line gastric cancer using apatinib with albumin-bound paclitaxel, with or without adebrelimab
This study tests whether adding adebrelimab to a regimen of apatinib and albumin-bound paclitaxel helps patients with advanced gastric or gastroesophageal junction cancer who did not respond to first-line therapy.
-
Ivoximab with Temozolomide for Relapsed Glioma
This trial tests whether adding ivoximab to temozolomide is safe and helps people whose glioma has come back or stopped responding to standard treatment.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.