Investigating health consequences in women with primary ovarian insufficiency
Prospective Cohort Study for Primary Ovarian Insufficient Patients in Clinical Reproductive Medicine Management System/Electronic Medical Record Cohort Database (CCRM/EMRCD)
This study is trying to learn more about the health effects of premature ovarian insufficiency in women by collecting health information and samples to see how it impacts their lives.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Female |
| Sponsor | The First Affiliated Hospital of Zhengzhou University Academic / other |
| Locations | 1 site (Zhengzhou, Henan) |
| Trial ID | NCT03989154 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on women diagnosed with premature ovarian insufficiency (POI), a condition affecting fertility and characterized by specific hormonal imbalances. Conducted at the Reproductive Medical Center of the First Affiliated Hospital of Zhengzhou University, the study aims to collect biological samples, questionnaires, and health data to understand both short- and long-term health outcomes associated with POI. By utilizing a comprehensive database of reproductive health, the study seeks to provide valuable insights into the prognosis of women suffering from this condition.
Who should consider this trial
Good fit: Ideal candidates for this study are women under 40 years of age who have experienced amenorrhea for at least four months and have specific hormonal test results indicating POI.
Not a fit: Patients who do not meet the age or hormonal criteria for primary ovarian insufficiency will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of the health implications of primary ovarian insufficiency, leading to better management and treatment options for affected women.
How similar studies have performed: While studies on reproductive health conditions exist, this specific focus on the long-term health consequences of primary ovarian insufficiency is relatively novel and underexplored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * younger than 40 years of age * at least four or more months of amenorrhea, two or more instances in which the serum FSH level is \> 40 U/L (i.e., two inspections at intervals of 1 month or more), with an oestradiol level of \<20pg/ml Exclusion Criteria: \-
Where this trial is running
Zhengzhou, Henan
- Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University — Zhengzhou, Henan, China (Recruiting)
Study contacts
- Study coordinator: Lanlan Fang, M.D.
- Email: fanglly@163.com
- Phone: 13673355291
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.