Investigating drug-resistant bacteria in Tunisian ICUs
Epidemiological Features of Emergent Highly Resistant Bacteria in Tunisian Intensive Care Units: A Prospective Multicenter National Observational Study (NOSOREA-3)
This study is trying to understand how drug-resistant bacteria are affecting patients in Tunisian intensive care units to help improve treatment and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Abderrahmane Mami Hospital Academic / other |
| Locations | 1 site (Ariana, Tunis) |
| Trial ID | NCT06392568 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the epidemiology, risk factors, and clinical impact of healthcare-associated infections caused by emergent highly drug-resistant pathogens in Tunisian intensive care units. It focuses particularly on carbapenem-resistant enterobacteriaceae and glycopeptide-resistant enterococcus. The study will involve a multicenter prospective collection of epidemiological records over a two-month period, following a previous point-prevalence study that highlighted the prevalence of these pathogens. The findings are expected to inform clinical practices and improve patient outcomes in critical care settings.
Who should consider this trial
Good fit: Ideal candidates for this study are adult patients admitted to intensive care units during the study period.
Not a fit: Patients who are not admitted to ICUs or are under 18 years old may not receive any benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management and treatment strategies for patients suffering from drug-resistant infections in intensive care units.
How similar studies have performed: Previous studies have shown significant findings regarding the prevalence of drug-resistant pathogens in healthcare settings, indicating that this approach is grounded in established research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult ICU patients admitted during the study period Exclusion Criteria: * none
Where this trial is running
Ariana, Tunis
- Abderrahmen Mami — Ariana, Tunis, Tunisia (Recruiting)
Study contacts
- Principal investigator: Amira JAMOUSSI, Professor — Abderrahmen Mami Hospital
- Study coordinator: Amira JAMOUSSI, Professor
- Email: amira.jamoussi@fmt.utm.tn
- Phone: +21698375250
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.