Investigating different types of coeliac disease
Official title: Genetic and Biological Background and Follow-up of Different Phenotypes of Coeliac Disease
Run by Tampere University Hospital · NCT05597904 · Data updated 2026-11-12
This study is trying to understand the different types of coeliac disease and dermatitis herpetiformis by looking at genetic and immune differences in patients and healthy people to help improve treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 3500 (estimated) |
| Sponsor | Tampere University Hospital Academic / other |
| Locations | 1 site (Tampere) |
| Status | Recruiting |
| Started | November 8, 2022 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2030 |
| Registry record updated | September 17, 2025 |
| Trial ID | NCT05597904 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with coeliac disease or dermatitis herpetiformis, as well as their healthy friends or non-related family members.
✕Probably not a fit
Patients under 18 years of age or those without a confirmed diagnosis of coeliac disease or dermatitis herpetiformis will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the genetic, serological, immunological, and microbiota differences among various phenotypes of coeliac disease and dermatitis herpetiformis. By recruiting patients with these conditions as well as healthy controls, the study will compare these factors to identify potential prognostic markers. The findings could lead to more personalized follow-up and treatment guidelines for individuals affected by coeliac disease. The research will focus on understanding the clinical heterogeneity of the disease and its implications for patient care.
Why it matters
Potential benefit: If successful, this study could lead to improved personalized treatment and management strategies for patients with coeliac disease.
How similar studies have gone: While the study addresses known heterogeneity in coeliac disease, the specific approach of comparing diverse phenotypes and their prognostic markers is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Cohorts 1 and 2: coeliac disease or dermatitis herpetiformis diagnosis * Cohort 3: friend or non-related family member of coeliac disease or dermatitis herpetiformis patient Exclusion Criteria: * Cohorts 1-3: Age \<18 years * Cohorts 1 and 2: coeliac disease or dermatitis herpetiformis diagnosis not confirmed * Cohort 3: coeliac disease or dermatitis herpetiformis diagnosis
Where it's running
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Tampere University Hospital
Tampere, Finland Recruiting
Study contacts
- Study coordinator: Teea T Salmi, Prof
- Email: teea.salmi@pshp.fi
- Phone: +358503016355
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.