Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating different types of coeliac disease

Official title: Genetic and Biological Background and Follow-up of Different Phenotypes of Coeliac Disease

Run by Tampere University Hospital · NCT05597904 · Data updated 2026-11-12

This study is trying to understand the different types of coeliac disease and dermatitis herpetiformis by looking at genetic and immune differences in patients and healthy people to help improve treatment options.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment3500 (estimated)
SponsorTampere University Hospital
Academic / other
Locations1 site (Tampere)
StatusRecruiting
StartedNovember 8, 2022
Main results expectedDecember 31, 2027
Study endsDecember 31, 2030
Registry record updatedSeptember 17, 2025
Trial IDNCT05597904 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals diagnosed with coeliac disease or dermatitis herpetiformis, as well as their healthy friends or non-related family members.

Probably not a fit

Patients under 18 years of age or those without a confirmed diagnosis of coeliac disease or dermatitis herpetiformis will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the genetic, serological, immunological, and microbiota differences among various phenotypes of coeliac disease and dermatitis herpetiformis. By recruiting patients with these conditions as well as healthy controls, the study will compare these factors to identify potential prognostic markers. The findings could lead to more personalized follow-up and treatment guidelines for individuals affected by coeliac disease. The research will focus on understanding the clinical heterogeneity of the disease and its implications for patient care.

Why it matters

Potential benefit: If successful, this study could lead to improved personalized treatment and management strategies for patients with coeliac disease.

How similar studies have gone: While the study addresses known heterogeneity in coeliac disease, the specific approach of comparing diverse phenotypes and their prognostic markers is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Cohorts 1 and 2: coeliac disease or dermatitis herpetiformis diagnosis
* Cohort 3: friend or non-related family member of coeliac disease or dermatitis herpetiformis patient

Exclusion Criteria:

* Cohorts 1-3: Age \<18 years
* Cohorts 1 and 2: coeliac disease or dermatitis herpetiformis diagnosis not confirmed
* Cohort 3: coeliac disease or dermatitis herpetiformis diagnosis

Where it's running

  • Tampere University Hospital
    Tampere, Finland
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.