Investigating childhood obesity and adipose tissue dysfunction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore how changes in adipose tissue biology contribute to obesity and related health issues in children and adolescents. Researchers will analyze adipose tissue samples from participants to identify mechanisms and molecular targets that lead to dysfunction. The study will assess various factors including tissue composition, inflammation, and metabolism, correlating these findings with clinical outcomes. The goal is to understand early alterations in adipose tissue that may predispose children to obesity.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* body weight: 3000 g - 180 kg
* suitable surgical procedure
* signed informed consent by the guardians and the study participant, if older 12 years

Exclusion Criteria:

* severe chronic and inflammatory diseases
* acute or chronic infections
* oncological diseases
* clotting disorders
* complications during surgical procedure
* drug treatment
* nil by mouth

Where it's running

• Center for Pediatric Research Leipzig (CPL)
  Leipzig, Saxony, Germany Recruiting

Study contacts

• Principal investigator: Antje Körner, Prof. Dr. — University of Leipzig
• Study coordinator: Antje Körner, Prof. Dr.
• Email: Antje.Koerner@medizin.uni-leipzig.de
• Phone: 0049/(0)341-9726854

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.