Investigating cardiovascular health differences between black and white patients
Multidisciplinary Approach to Reduce Cardiovascular Health Disparities in the Baltimore RAcial Minority CommunitiEs (M-BRACE Trial)
This study looks at how heart health differs between black and white patients who have serious blood flow problems to see if there are any important differences based on race.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | LifeBridge Health Academic / other |
| Locations | 1 site (Baltimore, Maryland) |
| Trial ID | NCT06168968 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the differences in thrombogenicity between black and white patients who are admitted with atherothrombotic events such as acute coronary syndrome, multi-vessel coronary artery disease, and ischemic stroke. Participants will undergo laboratory testing and health outcome assessments to gather data on these differences. The study seeks to identify potential disparities in cardiovascular health that may exist based on race.
Who should consider this trial
Good fit: Ideal candidates include patients aged 18 and older who are admitted with acute coronary syndrome, ischemic stroke, or multi-vessel coronary artery disease.
Not a fit: Patients who are pregnant, currently enrolled in another investigational trial, or have certain medical conditions such as neoplastic diseases or recent COVID-19 infection may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of cardiovascular health disparities among different racial groups.
How similar studies have performed: While this study addresses a critical area of health disparities, similar studies have shown varying degrees of success in understanding cardiovascular health differences, making this approach both relevant and necessary.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥18 years of age admitted with ACS, AIS, or multi-vessel CAD * Competent mental condition to provide informed consent and able to participate in follow-ups Exclusion Criteria: * Pregnant women * Currently enrolled in an investigational drug or device trial * Undergoing treatment for neoplastic, autoimmune, or connective tissue disease * COVID-19 infection within 30 days of enrollment * Known history of hepatitis or HIV * Deemed unfit to participate according to the investigator * Known history of drug abuse * Known platelet count of \<100,000/mm3 * Hematocrit \< 25%
Where this trial is running
Baltimore, Maryland
- Sinai Hospital of Baltimore — Baltimore, Maryland, United States (Recruiting)
Study contacts
- Study coordinator: Kevin Bliden, BS, MBA
- Email: kbliden@lifebridgehealth.org
- Phone: 4432441497
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.