Intraperitoneal spray plus IV lidocaine to reduce pain after laparoscopic myomectomy
Official title: The Impact of Intraperitoneal Spray Combined With Intravenous Lidocaine on Postoperative Pain After Myomectomy
Run by General Hospital of Ningxia Medical University · NCT07268495 · Data updated 2026-11-12
This will test whether using a lidocaine spray inside the abdomen plus IV lidocaine reduces pain after laparoscopic myomectomy in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | Women only |
| Enrollment | 100 (estimated) |
| Sponsor | General Hospital of Ningxia Medical University Academic / other |
| Locations | 1 site (Yinchuan, Ningxia) |
| Status | Recruiting |
| Started | August 1, 2024 |
| Main results expected | August 1, 2025 |
| Study ends | December 20, 2025 |
| Registry record updated | December 5, 2025 |
| Trial ID | NCT07268495 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–65 with ASA physical status I–III scheduled for laparoscopic myomectomy who can give informed consent and do not have severe organ disease, chronic pain, arrhythmia, or lidocaine allergy.
✕Probably not a fit
Patients with expected surgery durations over 3 hours, those converted to open surgery, those allergic to lidocaine, or those with severe hepatic/renal/cardiac disease, chronic pain, or arrhythmia are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults undergoing laparoscopic myomectomy under general anesthesia are assigned to one of four intraoperative treatments combining intravenous and intraperitoneal lidocaine or saline. Pain after surgery will be compared between the groups to see if the combined route lowers postoperative pain. Eligible participants are aged 18–65 with ASA I–III and provide informed consent, while those with long surgeries or certain comorbidities are excluded. The trial is conducted at the General Hospital of Ningxia Medical University in Yinchuan.
Why it matters
Potential benefit: If successful, the approach could reduce postoperative pain and lower the need for opioid pain medicines after laparoscopic myomectomy.
How similar studies have gone: Previous trials of either intravenous or intraperitoneal lidocaine in laparoscopic procedures have shown mixed but often favorable effects on postoperative pain.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age:18-65 years old; 2. ASA physical status classification I - III; 3. Undergoing laparoscopic hysteromyoma resection under general anesthesia; 4. The patient has been informed and has signed the informed consent form. Exclusion Criteria: 1. Surgery duration exceeding 3 hours; 2. Need for additional surgery; 3. Allergy to the study drugs; 4. Presence of severe psychological,hepatic,renal,and cardiac diseases; 5. History of chronic pain or arrhythmia. Elimination Criteria: 1. The patient or their family withdraws from or refuses to participate in the trial during the observation period; 2. Conversion from laparoscopy to laparotomy or change in surgical approach during the procedure.
Where it's running
-
General Hospital of Ningxia Medical University
Yinchuan, Ningxia, China Recruiting
Study contacts
- Study coordinator: Ma Hanxaing
- Email: mahanxiang@hotmail.com
- Phone: 86-13519591508
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.