Clinical trial Recruiting at 1 site Observational Ages 18 to 70

Intraoral scanning and CBCT for detecting dental plaque and cavities

Official title: Intra Oral Scan and CBCT Aided Diagnosis of Dental Plaque and Caries

Run by University Hospital, Ghent · NCT07555223 · Data updated 2026-11-12

This project tests whether intraoral scans and CBCT can accurately detect dental plaque and cavities in adults aged 18 to 70.

More Dental Caries trials

Quick facts

Study typeObservational
Ages18 Years to 70 Years
SexAll
Enrollment50 (estimated)
SponsorUniversity Hospital, Ghent
Academic / other
Locations1 site (Wondelgem, Botestraat)
StatusRecruiting
StartedApril 3, 2025
Main results expectedOctober 2026
Study endsJuly 2027
Registry record updatedApril 29, 2026
Trial IDNCT07555223 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults 18–70 years old who have at least 20 teeth, are not pregnant, and can give informed consent.

Probably not a fit

Patients with conditions that prevent proper intraoral examination (for example severe gag reflex or limited mouth opening), those with fewer than 20 teeth, pregnant people, or those unable to consent are unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective clinical study will use intraoral scans (including white-light imaging and caries-detection features) and CBCT to identify dental plaque and caries in adults. Plaque detection on IOS will be compared against plaque-disclosing agents, while caries detection on IOS and CBCT will be compared with conventional visual inspection and bitewing radiography. Participants must be able to tolerate an intraoral exam and have at least 20 teeth present. Diagnostic performance measures such as sensitivity and specificity will be calculated to compare the imaging approaches with current clinical reference standards.

Why it matters

Potential benefit: If successful, this could enable quicker, noninvasive digital checks for plaque and early cavities that improve detection and streamline dental care.

How similar studies have gone: Some prior studies have shown promise for intraoral scanners in detecting caries and plaque, but findings are mixed and combining CBCT for this purpose is less well established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18 to 70 years
* Not pregnant and not planning pregnant
* At least 20 teeth present
* Ability to provide informed consent

Exclusion Criteria:

* Conditions that prevent proper intraoral examination (e.g., severe gag reflex, limited mouth opening)
* patient unable to provide informed consent

Where it's running

  • Tandarts Praktijk VERVACK
    Wondelgem, Botestraat, Belgium
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.