Intervention to reduce alcohol use in young people with early phase psychosis
Piloting of an Intervention to Reduce Problematic Alcohol Use in Early Phase Psychosis
This study is testing a new therapy to see if it can help young people with early phase psychosis and alcohol problems improve their mental health and get back to school or work better than standard treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 16 Years to 35 Years |
| Sex | All |
| Sponsor | Nova Scotia Health Authority Academic / other |
| Locations | 1 site (Halifax, Nova Scotia) |
| Trial ID | NCT05365347 on ClinicalTrials.gov |
What this trial studies
This study aims to pilot cognitive enhancement therapy (CET) for individuals aged 16-35 with early phase psychosis (EPP) who also have problematic alcohol use. Participants will be randomized to receive either CET or standard treatment, which includes brief psychoeducation about substance use. The study will assess clinical outcomes as well as social determinants of health, such as return to school or work, to evaluate the effectiveness of the intervention. By focusing on both clinical and social recovery metrics, the study seeks to provide a comprehensive understanding of the impact of alcohol on recovery from psychosis.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 16-35 with a primary psychotic disorder and problematic alcohol use.
Not a fit: Patients with another substance use disorder, other than nicotine dependence, may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve recovery outcomes for young individuals with early phase psychosis by reducing alcohol consumption.
How similar studies have performed: Previous studies have indicated that addressing substance use in psychosis treatment can improve recovery outcomes, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * This study will enroll individuals 16-35 years of age from Early Intervention Services for Psychosis in Nova Scotia * less than 5 years of psychotic illness. * Individuals will have a psychotic spectrum diagnosis (primary psychotic disorder) that will include schizophrenia, schizoaffective disorder, and unspecified schizophrenia spectrum disorder. * have problematic alcohol use (score of 8 or higher on the World Health Organization Alcohol Use Disorders Identification Test (WHO-AUDIT)) Exclusion Criteria: * presence of another substance use disorder other than nicotine dependence
Where this trial is running
Halifax, Nova Scotia
- Nova Scotia Health Authority — Halifax, Nova Scotia, Canada (Recruiting)
Study contacts
- Principal investigator: Philip G Tibbo, MD — Nova Scotia Health Authority
- Study coordinator: Candice E Crocker, PhD
- Email: Candice.Crocker@nshealth.ca
- Phone: 902-473-3755
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.