Internet-delivered Emotion Regulation Therapy for Adolescents with NSSI
Official title: Internet-delivered Emotion Regulation Individual Therapy or Adolescents (IERITA) With Self-injury Within Child and Adolescent Mental Health Services
Run by Karolinska Institutet · NCT07573085 · Data updated 2026-11-12
This trial tests whether a flexible, internet-based therapy for teens who self-injure can be more effective than standard online treatment for reducing nonsuicidal self-injury symptoms.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 13 Years to 17 Years |
| Sex | All |
| Enrollment | 341 (estimated) |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 1 site (Stockholm) |
| Status | Recruiting |
| Started | May 22, 2026 |
| Main results expected | December 2029 |
| Study ends | December 2040 |
| Registry record updated | June 8, 2026 |
| Trial ID | NCT07573085 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adolescents aged 13-17 who have at least one self-injury episode in the past three months and have a parent willing to engage in the program.
✕Probably not a fit
youths with immediate suicide risk or with severe global impairment, or who are already receiving certain intensive therapies, may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adolescents with nonsuicidal self-injury are randomized to standard IERITA or an adaptable version that personalizes dose and delivery. All participants start with four weeks of standard IERITA, after which those unlikely to remit may switch to the adaptable format for the remaining weeks. The study collects data before, during, and after treatment, with extended follow-up up to ten years via public registers. The primary endpoint is at one month post-treatment, with a focus on reducing ongoing NSSI in the adolescent population. The trial is conducted within child and adolescent mental health services, led by Karolinska Institutet in collaboration with regional partners.
Why it matters
Potential benefit: If successful, adolescents who are not responding to standard treatment could see greater reductions in self-injury and improved emotion regulation through a personalized, internet-delivered approach.
How similar studies have gone: Earlier studies suggest digital, structured emotion-regulation therapies can reduce NSSI, but this adaptive approach in adolescents is novel and aims to optimize responders.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 13-17 years old * At least one self-injury episode in the past three months * A parent willing to engage in the parent program Exclusion Criteria: * Immediate suicide risk * Global functioning corresponding to a rating ≤40 of the Children's Global Assessment Scale (CGAS) * Social problems needing immediate intervention (e.g., violence within the family) * Ongoing dialectical behavior therapy for adolescents
Where it's running
-
Karolinska Institutet
Stockholm, Sweden Recruiting
Study contacts
- Principal investigator: Johan Bjureberg, PhD — Karolinska Institutet
- Study coordinator: Olivia Ojala, PhD
- Email: olivia.ojala@ki.se
- Phone: +46761426565
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.