Individualized exercise plan for kids with hypertrophic cardiomyopathy
Official title: Effects of Exercise Prescription on Cardiovascular Health and Quality of Life in Children With Hypertrophic Cardiomyopathy
Run by Alder Hey Children's NHS Foundation Trust · NCT07595354 · Data updated 2026-11-12
Aimed at children aged 10–18 with non-obstructive HCM, the study tests whether a personalized exercise prescription can be safely delivered and followed.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 10 Years to 18 Years |
| Sex | All |
| Enrollment | 10 (estimated) |
| Sponsor | Alder Hey Children's NHS Foundation Trust Academic / other |
| Locations | 1 site (Liverpool) |
| Status | Recruiting |
| Started | December 24, 2025 |
| Main results expected | March 2027 |
| Study ends | August 2027 |
| Registry record updated | May 19, 2026 |
| Trial ID | NCT07595354 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ages 10–18 with non-obstructive HCM under evaluation at Alder Hey, and who can maintain an exercise log with support.
✕Probably not a fit
Children with complex co-morbidities, mobility limitations, or those unable to participate in follow-up could see little or no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates delivering a customized exercise plan created by a team of clinicians to children with hypertrophic cardiomyopathy who have normal heart function. Participants will work with doctors, nurses, and physiotherapists to develop and implement an exercise prescription and will log their activity weekly with carer support. The goal is to determine feasibility, safety, and adherence to the personalized plan. The research is conducted at Alder Hey Children’s Hospital in Liverpool and focuses on non-obstructive HCM.
Why it matters
Potential benefit: If successful, children may gain safer, tailored exercise routines that support physical health and well-being.
How similar studies have gone: Previous work suggests exercise can be feasible for many with HCM when properly supervised, though this specific individualized prescription approach is being explored.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergoing screening for HCM due to a family history or gene-positive * Aged 10 to 18 years (inclusive) * Known to the inherited cardiac conditions clinic at Alder Hey Children's Hospital * Normal cardiac function * Able to complete an exercise log weekly with support from carers * Child or carer able to participate in telephone follow-up Exclusion Criteria: * Moderate to severe co-morbidities, including neuromuscular and respiratory illness and conditions affecting mobility * Learning difficulties precluding exercise participation * Phenotype of HCM * History of exercise-induced arrhythmia and/or syncope * History of unexplained syncope * Patients with an implantable cardiac defibrillator (ICD) * Family History of sudden cardiac death in first-degree relative * Child or carer unable to comply with telephone follow-up
Where it's running
-
Alder Hey Children's Hospital
Liverpool, United Kingdom Recruiting
Study contacts
- Study coordinator: Sophia Khan, MbChB MD(Res)
- Email: sophia.khan@alderhey.nhs.uk
- Phone: =447557356755
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.