Long-term outcomes for children with Hirschsprung's disease and anorectal malformations

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the long-term qualitative and quantitative outcomes of children diagnosed with Hirschsprung's disease and anorectal malformations. It will involve approximately 340 children who have undergone surgical treatment since 1991, focusing on the variability in surgical techniques and their impact on health outcomes. The study seeks to address the lack of comprehensive data on the effectiveness of different management strategies and the long-term quality of life for these patients. By collecting standardized outcome measures, the research aims to provide clearer prognostic information for families.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All children treated at either center with histologically confirmed Hirschsprung's Disease since diagnosis from 1991
* All children diagnosed with anorectal malformation on the basis of position in relation to the external sphincter and size

Exclusion Criteria:

* Patients with non-histologically diagnosed Hirschsprung's Disease
* Patients whose initial primary treatment or majority of follow-up for either condition has been external to either center
* Patients with funnel anus
* Adults who are unable to consent for themselves

Where it's running

• Alder Hey Children's Hospital
  Liverpool, Merseyside, United Kingdom Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.