Increasing HPV vaccination among middle and high school students in Auvergne-Rhône-Alpes
Official title: Prospective, Randomized, Cluster-controlled, Multicenter Study to Evaluate the Impact of an HPV Primary Prevention Intervention on HPV Vaccination Rates Among Adolescents in the AuRA Region.
Run by Centre Leon Berard · NCT07414719 · Data updated 2026-11-12
This project will try a school-based HPV prevention program to see if it increases vaccination rates among 11–17-year-old students in the Auvergne-Rhône-Alpes region.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 11 Years to 17 Years |
| Sex | All |
| Enrollment | 1422 (estimated) |
| Sponsor | Centre Leon Berard Academic / other |
| Locations | 1 site (Saint-Priest) |
| Status | Recruiting |
| Started | December 16, 2025 |
| Main results expected | June 30, 2027 |
| Study ends | June 30, 2027 |
| Registry record updated | February 17, 2026 |
| Trial ID | NCT07414719 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are boys and girls aged 11–17 who attend participating public middle or high school classes in the Auvergne-Rhône-Alpes region, can read French, are affiliated with social security, and for whom parents have not expressed non-objection.
✕Probably not a fit
Students who are already fully vaccinated against HPV, who do not attend participating schools, whose parents object, who cannot read French, or who are legally protected and excluded from the protocol are unlikely to gain vaccination benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The program delivers a co-developed primary prevention intervention (HPV animation) in participating middle and high school classes. The intervention is implemented with input from local stakeholders and delivered to students and supervising teachers at selected public schools. Vaccination uptake among 11–17-year-olds will be measured at six months after the intervention to determine any change in HPV vaccine coverage. The study targets routine school settings in the AuRA region and documents consent and parental non-objection per French regulations.
Why it matters
Potential benefit: If successful, the intervention could raise HPV vaccination coverage among adolescents in the region and help reduce future HPV-related cancers.
How similar studies have gone: Previous school-based education and outreach programs have increased HPV vaccine uptake in several settings, although results depend on local implementation and context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria for children : * Girl or boy, student at a public school participating in the study * Aged 11 to 17 * Having received an information sheet about the study and having signed a declaration of non-objection * Whose parents have also received an information sheet and have not expressed their non-objection * Able to read, write, and understand French * Affiliated with the SS or equivalent Exclusion Criteria for children: * children protected by the law Inclusion Criteria for teachers : * Male or female, teacher at a public school participating in the study and supervising a participating class * Aged 18 or over * Having received an information sheet about the study and not having expressed their opposition * Able to read, write, and understand French * Affiliated with the SS or equivalent Exclusion Criteria for teachers : \- Person specially protected by law
Where it's running
-
Lycée BELTRAME
Saint-Priest, France Recruiting
Study contacts
- Study coordinator: Carmen DUPUIS, PhD
- Email: carmen.dupuis@lyon.unicancer.fr
- Phone: 0469856218
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.