Increasing HPV vaccination among middle and high school students in Auvergne-Rhône-Alpes
Prospective, Randomized, Cluster-controlled, Multicenter Study to Evaluate the Impact of an HPV Primary Prevention Intervention on HPV Vaccination Rates Among Adolescents in the AuRA Region.
This project will try a school-based HPV prevention program to see if it increases vaccination rates among 11–17-year-old students in the Auvergne-Rhône-Alpes region.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 1422 (estimated) |
| Ages | 11 Years to 17 Years |
| Sex | All |
| Sponsor | Centre Leon Berard Academic / other |
| Locations | 1 site (Saint-Priest) |
| Trial ID | NCT07414719 on ClinicalTrials.gov |
What this trial studies
The program delivers a co-developed primary prevention intervention (HPV animation) in participating middle and high school classes. The intervention is implemented with input from local stakeholders and delivered to students and supervising teachers at selected public schools. Vaccination uptake among 11–17-year-olds will be measured at six months after the intervention to determine any change in HPV vaccine coverage. The study targets routine school settings in the AuRA region and documents consent and parental non-objection per French regulations.
Who should consider this trial
Good fit: Ideal participants are boys and girls aged 11–17 who attend participating public middle or high school classes in the Auvergne-Rhône-Alpes region, can read French, are affiliated with social security, and for whom parents have not expressed non-objection.
Not a fit: Students who are already fully vaccinated against HPV, who do not attend participating schools, whose parents object, who cannot read French, or who are legally protected and excluded from the protocol are unlikely to gain vaccination benefit from participation.
Why it matters
Potential benefit: If successful, the intervention could raise HPV vaccination coverage among adolescents in the region and help reduce future HPV-related cancers.
How similar studies have performed: Previous school-based education and outreach programs have increased HPV vaccine uptake in several settings, although results depend on local implementation and context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria for children : * Girl or boy, student at a public school participating in the study * Aged 11 to 17 * Having received an information sheet about the study and having signed a declaration of non-objection * Whose parents have also received an information sheet and have not expressed their non-objection * Able to read, write, and understand French * Affiliated with the SS or equivalent Exclusion Criteria for children: * children protected by the law Inclusion Criteria for teachers : * Male or female, teacher at a public school participating in the study and supervising a participating class * Aged 18 or over * Having received an information sheet about the study and not having expressed their opposition * Able to read, write, and understand French * Affiliated with the SS or equivalent Exclusion Criteria for teachers : \- Person specially protected by law
Where this trial is running
Saint-Priest
- Lycée BELTRAME — Saint-Priest, France (Recruiting)
Study contacts
- Study coordinator: Carmen DUPUIS, PhD
- Email: carmen.dupuis@lyon.unicancer.fr
- Phone: 0469856218
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.