Increasing Cardiac Rehabilitation Attendance After a Secondary MI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center pilot randomized trial evaluates a low-risk behavioral intervention aimed at improving participation in cardiac rehabilitation after a secondary/type 2 myocardial infarction. Participants are randomized to receive clinician-focused messaging about referral and a motivational interviewing call to the patient, or usual care. Follow-up for 140 days includes remote check-ins and electronic health record review to measure attendance, clinical events, medication use, and patient-reported health status. Safety monitoring is ongoing to detect any adverse events related to the intervention. The study focuses on whether increased engagement with CR can translate into higher attendance and completion rates.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Inpatient at MGH with an index likely or confirmed secondary MI
* Primary care provider (PCP) within the Mass General Brigham (MGB) network with at least one visit in the past 2 years
* Anticipated ability to ambulate independently without walking aids or supplemental ambulatory oxygen at discharge
* Ability to provide informed consent

Exclusion Criteria:

* Known severe untreated valvular heart disease or severe prosthetic valve dysfunction
* Known hypertrophic obstructive cardiomyopathy
* End-stage heart failure (VAD, transplant patient, or undergoing evaluation for VAD or transplant)
* Hemodynamic instability at the time of pre-screening
* Terminal illness with life expectancy \< 1 year
* Severe anemia (hemoglobin \< 8 g/dL) at the time of pre-screening
* Active, unstable cancer (excluding non-metastatic skin cancer) or currently receiving intensive cancer therapy
* Advanced kidney disease requiring renal replacement therapy
* Receiving palliative or comfort care only
* Recurrent falls (≥2) or falls with injury in the past year
* Physical or cognitive impairment likely to prevent safe participation in exercise over the next 5 months (e.g., significant stroke deficits, dementia)
* High-risk for non-adherence to study requirements
* Incarcerated individuals
* Currently pregnant or within 3 months postpartum
* Previously referred to or participated in CR within the past year
* Alternative MI subtype (spontaneous \[type 1 MI\] or procedural MI \[type 4 or 5 MI\]) in the past 6 months
* Suspected or confirmed coronary mechanism of index MI (vasospasm, embolism, or spontaneous coronary artery dissection)
* Anticipated discharge or discharged before enrollment measures can be completed
* Anticipated discharge to a facility where independent participation in CR is not feasible
* Previously enrolled in or declined participation in this study

Where it's running

• Massachusetts General Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Cian P McCarthy, MB, BCh, BAO, SM — Massachusetts General Hospital
• Study coordinator: Cian McCarthy, MB, BCh, BAO, SM
• Email: CMCCARTHY37@MGB.ORG
• Phone: 617-726-2000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.