Improving tests for platelet function disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the diagnostic accuracy of new platelet function tests in patients with confirmed or suspected platelet function disorders. Participants will be recruited from the Coagulation Unit at Karolinska University Hospital and the Pediatric Coagulation Unit at Astrid Lindgren Children's Hospital. The goal is to enhance the effectiveness of platelet function testing during bleeding investigations, which could lead to better diagnosis and management of these disorders.

Why it matters

Who can join: the full rules

Inclusion Criteria, known defects:

* Known platelet function disorder under follow-up at Karolinska University Hospital (genetic or functional assay)
* High likelihood of platelet function disorder (aberrant screening test with inheritance)
* Family investigation for platelet disorder

Exclusion Criteria, known defects::

* Antiplatelet or anticoagulant drugs
* vWF:GPIb below 0.40 IU/mL
* Hematocrit below 0.35 or above 0.50
* Other coagulation disorder

Inclusion Criteria, suspected platelet function disorder:

* Bleeding investigation at Karolinska University Hospital

Exclusion Criteria, suspected platelet function disorder::

* Antiplatelet or anticoagulant drugs
* vWF:GPIb below 0.40 IU/mL
* Hematocrit below 0.35 or above 0.50
* Other coagulation disorder

Where it's running

• Karolinska University Hospital
  Stockholm, Sweden Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.